Phosphine-free Stille-Migita chemistry for the mild and orthogonal modification of DNA and RNA

An optimized catalyst system of [Pd2(dba)3] and AsPh3 efficiently catalyzes the Stille reaction between a diverse set of functionalized stannanes and halogenated mono-, di- and oligonucleotides. The methodology allows for the facile conjugation of short and long nucleic acid molecules with moieties...

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Main Authors: Krause, André (Author) , Muttach, Fabian (Author) , Jäschke, Andres (Author)
Format: Article (Journal)
Language:English
Published: 16 October 2014
In: Chemistry - a European journal
Year: 2014, Volume: 20, Issue: 50, Pages: 16613-16619
ISSN:1521-3765
DOI:10.1002/chem.201404843
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/chem.201404843
Verlag, lizenzpflichtig, Volltext: https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/chem.201404843
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Author Notes:André Krause, Alexander Hertl, Fabian Muttach, Andres Jäschke

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