Object recognition deficit in early- and adult-onset schizophrenia regardless of age at disease onset
Perceptual closure is the ability of the brain to recognize a complete object based on fragmentary information and has been known to be impaired in schizophrenia. Here, the neural integrity of perceptual closure in schizophrenia with different disease onsets was evaluated by examining the generation...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
17 October 2013
|
| In: |
Psychiatry research. Neuroimaging
Year: 2013, Jahrgang: 214, Heft: 3, Pages: 452-458 |
| ISSN: | 1872-7506 |
| DOI: | 10.1016/j.pscychresns.2013.08.010 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.pscychresns.2013.08.010 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0925492713002230 
|
| Verfasserangaben: | Hedieh Azadmehr, André Rupp, Martin Andermann, Dinka Pavicic, Kerstin Herwig, Matthias Weisbrod, Franz Resch, Rieke Oelkers-Ax |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 173650195X | ||
| 003 | DE-627 | ||
| 005 | 20220819000806.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 201023s2013 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.pscychresns.2013.08.010 |2 doi | |
| 035 | |a (DE-627)173650195X | ||
| 035 | |a (DE-599)KXP173650195X | ||
| 035 | |a (OCoLC)1341374760 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Azadmehr, Hedieh |d 1976- |e VerfasserIn |0 (DE-588)1020001186 |0 (DE-627)691070601 |0 (DE-576)35799941X |4 aut | |
| 245 | 1 | 0 | |a Object recognition deficit in early- and adult-onset schizophrenia regardless of age at disease onset |c Hedieh Azadmehr, André Rupp, Martin Andermann, Dinka Pavicic, Kerstin Herwig, Matthias Weisbrod, Franz Resch, Rieke Oelkers-Ax |
| 264 | 1 | |c 17 October 2013 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 23.10.2020 | ||
| 520 | |a Perceptual closure is the ability of the brain to recognize a complete object based on fragmentary information and has been known to be impaired in schizophrenia. Here, the neural integrity of perceptual closure in schizophrenia with different disease onsets was evaluated by examining the generation of event-related potential (ERP) components (P100, N180, and Ncl). ERPs were recorded from 40 patients (19 early-onset schizophrenia, “EOS” and 21 adult-onset schizophrenia, “AOS”) and 40 age-matched healthy volunteers. Brain electric source analysis (BESA) was applied to localize the cerebral generators underlying perceptual closure. Patients showed an impaired generation of Ncl and P100 components. P100 and Ncl amplitudes were significantly reduced in both AOS and EOS (P<0.01). Moreover, N180 and Ncl amplitudes were significantly increased with age in controls and patients (P<0.01). In the case of the Ncl, there was also a significant interaction (P<0.001) between age and group, indicating a greater age-dependent Ncl increase in controls compared to patients. Visual information processing during perceptual closure is impaired in schizophrenia, regardless of age at disease onset. The combined influence of age and group on the amplitude of the Ncl might support the idea of neurodevelopmental deficits in schizophrenia. | ||
| 650 | 4 | |a Closure negativity () | |
| 650 | 4 | |a Perceptual closure | |
| 700 | 1 | |a Rupp, André |d 1962- |e VerfasserIn |0 (DE-588)121268527 |0 (DE-627)705347079 |0 (DE-576)181320827 |4 aut | |
| 700 | 1 | |a Andermann, Martin |d 1983- |e VerfasserIn |0 (DE-588)1081427817 |0 (DE-627)846103508 |0 (DE-576)454395639 |4 aut | |
| 700 | 1 | |a Pavicic, Dinka |e VerfasserIn |4 aut | |
| 700 | 1 | |a Herwig, Kerstin |e VerfasserIn |4 aut | |
| 700 | 1 | |a Weisbrod, Matthias |d 1960- |e VerfasserIn |0 (DE-588)1018045562 |0 (DE-627)690499647 |0 (DE-576)170710211 |4 aut | |
| 700 | 1 | |a Resch, Franz |d 1953- |e VerfasserIn |0 (DE-588)136669972 |0 (DE-627)585458170 |0 (DE-576)301199612 |4 aut | |
| 700 | 1 | |a Oelkers-Ax, Rieke |e VerfasserIn |0 (DE-588)131676911 |0 (DE-627)512406677 |0 (DE-576)298666995 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Psychiatry research. Neuroimaging |d Amsterdam : Elsevier, 1990 |g 214(2013), 3, Seite 452-458 |h Online-Ressource |w (DE-627)894201530 |w (DE-600)2900605-3 |w (DE-576)491161778 |x 1872-7506 |7 nnas |a Object recognition deficit in early- and adult-onset schizophrenia regardless of age at disease onset |
| 773 | 1 | 8 | |g volume:214 |g year:2013 |g number:3 |g pages:452-458 |g extent:7 |a Object recognition deficit in early- and adult-onset schizophrenia regardless of age at disease onset |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.pscychresns.2013.08.010 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/article/pii/S0925492713002230 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20201023 | ||
| 993 | |a Article | ||
| 994 | |a 2013 | ||
| 998 | |g 131676911 |a Oelkers-Ax, Rieke |m 131676911:Oelkers-Ax, Rieke |d 910000 |d 910600 |d 50000 |e 910000PO131676911 |e 910600PO131676911 |e 50000PO131676911 |k 0/910000/ |k 1/910000/910600/ |k 0/50000/ |p 8 |y j | ||
| 998 | |g 136669972 |a Resch, Franz |m 136669972:Resch, Franz |d 910000 |d 910600 |d 50000 |e 910000PR136669972 |e 910600PR136669972 |e 50000PR136669972 |k 0/910000/ |k 1/910000/910600/ |k 0/50000/ |p 7 | ||
| 998 | |g 1018045562 |a Weisbrod, Matthias |m 1018045562:Weisbrod, Matthias |d 910000 |d 910600 |d 50000 |e 910000PW1018045562 |e 910600PW1018045562 |e 50000PW1018045562 |k 0/910000/ |k 1/910000/910600/ |k 0/50000/ |p 6 | ||
| 998 | |g 1081427817 |a Andermann, Martin |m 1081427817:Andermann, Martin |d 910000 |d 911100 |e 910000PA1081427817 |e 911100PA1081427817 |k 0/910000/ |k 1/910000/911100/ |p 3 | ||
| 998 | |g 121268527 |a Rupp, André |m 121268527:Rupp, André |d 910000 |d 911100 |d 50000 |e 910000PR121268527 |e 911100PR121268527 |e 50000PR121268527 |k 0/910000/ |k 1/910000/911100/ |k 0/50000/ |p 2 | ||
| 998 | |g 1020001186 |a Azadmehr, Hedieh |m 1020001186:Azadmehr, Hedieh |p 1 |x j | ||
| 999 | |a KXP-PPN173650195X |e 378548335X | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"type":{"bibl":"periodical","media":"Online-Ressource"},"physDesc":[{"extent":"Online-Ressource"}],"disp":"Object recognition deficit in early- and adult-onset schizophrenia regardless of age at disease onsetPsychiatry research. Neuroimaging","part":{"issue":"3","volume":"214","extent":"7","text":"214(2013), 3, Seite 452-458","year":"2013","pages":"452-458"},"title":[{"title_sort":"Psychiatry research","title":"Psychiatry research","partname":"Neuroimaging : the official publication of the International Society for Neuroimaging in Psychiatry"}],"language":["eng"],"id":{"zdb":["2900605-3"],"eki":["894201530"],"issn":["1872-7506"]},"pubHistory":["Volume 35, issue 1 (1990)-"],"origin":[{"publisher":"Elsevier","dateIssuedDisp":"[1990]-","publisherPlace":"Amsterdam"}],"note":["Gesehen am 24.03.2023"],"recId":"894201530"}],"recId":"173650195X","note":["Gesehen am 23.10.2020"],"origin":[{"dateIssuedKey":"2013","dateIssuedDisp":"17 October 2013"}],"id":{"doi":["10.1016/j.pscychresns.2013.08.010"],"eki":["173650195X"]},"physDesc":[{"extent":"7 S."}],"title":[{"title_sort":"Object recognition deficit in early- and adult-onset schizophrenia regardless of age at disease onset","title":"Object recognition deficit in early- and adult-onset schizophrenia regardless of age at disease onset"}],"person":[{"family":"Azadmehr","display":"Azadmehr, Hedieh","given":"Hedieh","role":"aut"},{"display":"Rupp, André","given":"André","role":"aut","family":"Rupp"},{"family":"Andermann","role":"aut","given":"Martin","display":"Andermann, Martin"},{"display":"Pavicic, Dinka","given":"Dinka","role":"aut","family":"Pavicic"},{"family":"Herwig","given":"Kerstin","display":"Herwig, Kerstin","role":"aut"},{"family":"Weisbrod","role":"aut","display":"Weisbrod, Matthias","given":"Matthias"},{"family":"Resch","role":"aut","given":"Franz","display":"Resch, Franz"},{"role":"aut","display":"Oelkers-Ax, Rieke","given":"Rieke","family":"Oelkers-Ax"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"language":["eng"],"name":{"displayForm":["Hedieh Azadmehr, André Rupp, Martin Andermann, Dinka Pavicic, Kerstin Herwig, Matthias Weisbrod, Franz Resch, Rieke Oelkers-Ax"]}} | ||
| SRT | |a AZADMEHRHEOBJECTRECO1720 | ||