Knowledge gaps in oncoplastic breast surgery
The aims of the Oncoplastic Breast Consortium initiative were to identify important knowledge gaps in the field of oncoplastic breast-conserving surgery and nipple-sparing or skin-sparing mastectomy with immediate breast reconstruction, and to recommend appropriate research strategies to address the...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
3 August 2020
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| In: |
The lancet. Oncology
Year: 2020, Jahrgang: 21, Heft: 8, Pages: e375-e385 |
| ISSN: | 1474-5488 |
| DOI: | 10.1016/S1470-2045(20)30084-X |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1016/S1470-2045(20)30084-X Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S147020452030084X 
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| Verfasserangaben: | Walter P Weber, Monica Morrow, Jana de Boniface, Andrea Pusic, Giacomo Montagna, Elisabeth A Kappos, Mathilde Ritter, Martin Haug, Christian Kurzeder, Ramon Saccilotto, Alexandra Schulz, John Benson, Florian Fitzal, Zoltan Matrai, Jane Shaw, Marie-Jeanne Vrancken Peeters, Shelley Potter, Joerg Heil, on behalf of the Oncoplastic Breast Consortium |
| Zusammenfassung: | The aims of the Oncoplastic Breast Consortium initiative were to identify important knowledge gaps in the field of oncoplastic breast-conserving surgery and nipple-sparing or skin-sparing mastectomy with immediate breast reconstruction, and to recommend appropriate research strategies to address these gaps. A total of 212 surgeons and 26 patient advocates from 55 countries prioritised the 15 most important knowledge gaps from a list of 38 in two electronic Delphi rounds. An interdisciplinary panel of the Oncoplastic Breast Consortium consisting of 63 stakeholders from 20 countries obtained consensus during an in-person meeting to select seven of these 15 knowledge gaps as research priorities. Three key recommendations emerged from the meeting. First, the effect of oncoplastic breast-conserving surgery on quality of life and the optimal type and timing of reconstruction after nipple-sparing or skin-sparing mastectomy with planned radiotherapy should be addressed by prospective cohort studies at an international level. Second, the role of adjunctive mesh and the positioning of implants during implant-based breast reconstruction should ideally be investigated by randomised controlled trials of pragmatic design. Finally, the BREAST-Q questionnaire is a suitable tool to assess primary outcomes in these studies, but other metrics to measure patient-reported outcomes should be systematically evaluated and quality indicators of surgical morbidity should be further assessed. |
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| Beschreibung: | Gesehen am 26.10.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1474-5488 |
| DOI: | 10.1016/S1470-2045(20)30084-X |