Primary multivessel occlusions treated with mechanical thrombectomy
Background and Purpose: Acute ischemic stroke caused by primary multivessel occlusions (pMVO) is a rare but devastating disease. Whether multi-target mechanical thrombectomy for pMVO is beneficial remains unknown. Methods: Multicenter retrospective review of patients treated with multi-target mechan...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
13 Jul 2020
|
| In: |
Stroke
Year: 2020, Jahrgang: 51, Heft: 9, Pages: e232-e237 |
| ISSN: | 1524-4628 |
| DOI: | 10.1161/STROKEAHA.120.029629 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1161/STROKEAHA.120.029629 Verlag, lizenzpflichtig, Volltext: https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.029629 
|
| Verfasserangaben: | Kaesmacher Johannes, Meyer Lukas, Styczen Hanna, Lobsien Donald, Seker Fatih, Piechowiak Eike, Tan Benjamin Y.Q., Fischer Sebastian, Clajus Christin, Yeo Leonard, Papanagiotou Panagiotis, Kastrup Andreas, Maegerlein Christian, Wunderlich Silke, Möhlenbruch Markus A., Radbruch Alexander, Gralla Jan, Fiehler Jens, Maus Volker |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1737351277 | ||
| 003 | DE-627 | ||
| 005 | 20220830084528.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 201029s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1161/STROKEAHA.120.029629 |2 doi | |
| 035 | |a (DE-627)1737351277 | ||
| 035 | |a (DE-599)KXP1737351277 | ||
| 035 | |a (OCoLC)1341375151 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Kaesmacher, Johannes |d 1988- |e VerfasserIn |0 (DE-588)1220442798 |0 (DE-627)1737352974 |4 aut | |
| 245 | 1 | 0 | |a Primary multivessel occlusions treated with mechanical thrombectomy |c Kaesmacher Johannes, Meyer Lukas, Styczen Hanna, Lobsien Donald, Seker Fatih, Piechowiak Eike, Tan Benjamin Y.Q., Fischer Sebastian, Clajus Christin, Yeo Leonard, Papanagiotou Panagiotis, Kastrup Andreas, Maegerlein Christian, Wunderlich Silke, Möhlenbruch Markus A., Radbruch Alexander, Gralla Jan, Fiehler Jens, Maus Volker |
| 264 | 1 | |c 13 Jul 2020 | |
| 300 | |a 6 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 29.10.2020 | ||
| 520 | |a Background and Purpose: Acute ischemic stroke caused by primary multivessel occlusions (pMVO) is a rare but devastating disease. Whether multi-target mechanical thrombectomy for pMVO is beneficial remains unknown. Methods: Multicenter retrospective review of patients treated with multi-target mechanical thrombectomy. The following pMVO sites were included: basilar artery, internal carotid artery, and middle cerebral artery (M1 and M2). Baseline characteristics were reported together with interventional technique, technical efficacy, and safety parameters. Clinical outcomes were evaluated applying the National Institutes of Health Stroke Scale and modified Rankin Scale. A systematic literature review was performed to summarize previous reports on pMVO mechanical thrombectomy. Results: Of 6081 patients screened, 21 patients met the inclusion criteria (0.35% [95% CI, 0.23%-0.53%]). In 70% (14/20) a cardioembolic cause was reported. A successful reperfusion of Thrombolysis in Cerebral Infarction scale score ≥2b was achieved in 95.2% (20/21) for the first and 76.1% (16/21) for the second target vessel. In those who survived the acute hospital stay (n=10/21), median admission National Institutes of Health Stroke Scale improved from 21 (interquartile range, 13-27) to 8 (interquartile range, 2-20) at discharge (P=0.006). Mortality was 60% (12/20) at 90 days and only 20% (4/20) of patients reached modified Rankin Scale score ≤2. Acceptable outcomes were almost exclusively observed in pMVO patients presenting with at least one M2 occlusion.Conclusions: Multi-target mechanical thrombectomy for pMVOs is rarely performed; however, the procedure appears to be feasible and safe with high reperfusion rates for both occlusion sites. More than half of all treated patients deceased early and favorable outcomes may only be expected for pMVO patients including at least one M2 occlusion. | ||
| 700 | 1 | |a Meyer, Lukas |d 1989- |e VerfasserIn |0 (DE-588)118975889X |0 (DE-627)1668459132 |4 aut | |
| 700 | 1 | |a Styczen, Hanna |e VerfasserIn |4 aut | |
| 700 | 1 | |a Lobsien, Donald |e VerfasserIn |4 aut | |
| 700 | 1 | |a Seker, Fatih |d 1987- |e VerfasserIn |0 (DE-588)1062998995 |0 (DE-627)807100420 |0 (DE-576)420347895 |4 aut | |
| 700 | 1 | |a Piechowiak, Eike |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tan, Benjamin Y.Q. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Fischer, Sebastian |e VerfasserIn |4 aut | |
| 700 | 1 | |a Clajus, Christin |e VerfasserIn |4 aut | |
| 700 | 1 | |a Yeo, Leonard |e VerfasserIn |4 aut | |
| 700 | 1 | |a Papanagiotou, Panagiotis |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kastrup, Andreas |e VerfasserIn |4 aut | |
| 700 | 1 | |a Maegerlein, Christian |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wunderlich, Silke |e VerfasserIn |4 aut | |
| 700 | 1 | |a Möhlenbruch, Markus Alfred |d 1979- |e VerfasserIn |0 (DE-588)137693591 |0 (DE-627)594845041 |0 (DE-576)304845655 |4 aut | |
| 700 | 1 | |a Radbruch, Alexander |d 1977- |e VerfasserIn |0 (DE-588)1022344501 |0 (DE-627)716953951 |0 (DE-576)362851166 |4 aut | |
| 700 | 1 | |a Gralla, Jan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Fiehler, Jens |e VerfasserIn |4 aut | |
| 700 | 1 | |a Maus, Volker |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Stroke |d New York, NY : Association, 1970 |g 51(2020), 9, Seite e232-e237 |h Online-Ressource |w (DE-627)266879985 |w (DE-600)1467823-8 |w (DE-576)075145731 |x 1524-4628 |7 nnas |a Primary multivessel occlusions treated with mechanical thrombectomy |
| 773 | 1 | 8 | |g volume:51 |g year:2020 |g number:9 |g pages:e232-e237 |g extent:6 |a Primary multivessel occlusions treated with mechanical thrombectomy |
| 856 | 4 | 0 | |u https://doi.org/10.1161/STROKEAHA.120.029629 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.029629 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20201029 | ||
| 993 | |a Article | ||
| 994 | |a 2020 | ||
| 998 | |g 1022344501 |a Radbruch, Alexander |m 1022344501:Radbruch, Alexander |d 50000 |e 50000PR1022344501 |k 0/50000/ |p 16 | ||
| 998 | |g 137693591 |a Möhlenbruch, Markus Alfred |m 137693591:Möhlenbruch, Markus Alfred |d 910000 |d 911100 |d 50000 |e 910000PM137693591 |e 911100PM137693591 |e 50000PM137693591 |k 0/910000/ |k 1/910000/911100/ |k 0/50000/ |p 15 | ||
| 998 | |g 1062998995 |a Seker, Fatih |m 1062998995:Seker, Fatih |d 910000 |d 911100 |e 910000PS1062998995 |e 911100PS1062998995 |k 0/910000/ |k 1/910000/911100/ |p 5 | ||
| 999 | |a KXP-PPN1737351277 |e 3789093807 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"note":["Gesehen am 29.10.2020"],"recId":"1737351277","person":[{"family":"Kaesmacher","role":"aut","given":"Johannes","display":"Kaesmacher, Johannes"},{"given":"Lukas","display":"Meyer, Lukas","family":"Meyer","role":"aut"},{"given":"Hanna","display":"Styczen, Hanna","family":"Styczen","role":"aut"},{"display":"Lobsien, Donald","given":"Donald","role":"aut","family":"Lobsien"},{"role":"aut","family":"Seker","given":"Fatih","display":"Seker, Fatih"},{"display":"Piechowiak, Eike","given":"Eike","role":"aut","family":"Piechowiak"},{"display":"Tan, Benjamin Y.Q.","given":"Benjamin Y.Q.","role":"aut","family":"Tan"},{"display":"Fischer, Sebastian","given":"Sebastian","family":"Fischer","role":"aut"},{"given":"Christin","display":"Clajus, Christin","family":"Clajus","role":"aut"},{"family":"Yeo","role":"aut","given":"Leonard","display":"Yeo, Leonard"},{"family":"Papanagiotou","role":"aut","given":"Panagiotis","display":"Papanagiotou, Panagiotis"},{"given":"Andreas","display":"Kastrup, Andreas","role":"aut","family":"Kastrup"},{"display":"Maegerlein, Christian","given":"Christian","family":"Maegerlein","role":"aut"},{"role":"aut","family":"Wunderlich","given":"Silke","display":"Wunderlich, Silke"},{"family":"Möhlenbruch","role":"aut","display":"Möhlenbruch, Markus Alfred","given":"Markus Alfred"},{"role":"aut","family":"Radbruch","given":"Alexander","display":"Radbruch, Alexander"},{"given":"Jan","display":"Gralla, Jan","family":"Gralla","role":"aut"},{"given":"Jens","display":"Fiehler, Jens","family":"Fiehler","role":"aut"},{"given":"Volker","display":"Maus, Volker","role":"aut","family":"Maus"}],"name":{"displayForm":["Kaesmacher Johannes, Meyer Lukas, Styczen Hanna, Lobsien Donald, Seker Fatih, Piechowiak Eike, Tan Benjamin Y.Q., Fischer Sebastian, Clajus Christin, Yeo Leonard, Papanagiotou Panagiotis, Kastrup Andreas, Maegerlein Christian, Wunderlich Silke, Möhlenbruch Markus A., Radbruch Alexander, Gralla Jan, Fiehler Jens, Maus Volker"]},"language":["eng"],"origin":[{"dateIssuedDisp":"13 Jul 2020","dateIssuedKey":"2020"}],"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"id":{"eki":["266879985"],"issn":["1524-4628"],"zdb":["1467823-8"]},"title":[{"title_sort":"Stroke","subtitle":"journal of the American Heart Association","title":"Stroke"}],"origin":[{"dateIssuedDisp":"1970-","publisher":"Association ; Lippincott Williams & Wilkins","publisherPlace":"New York, NY ; Philadelphia, Pa.","dateIssuedKey":"1970"}],"recId":"266879985","corporate":[{"display":"American Heart Association","role":"isb"}],"disp":"Primary multivessel occlusions treated with mechanical thrombectomyStroke","type":{"media":"Online-Ressource","bibl":"periodical"},"part":{"year":"2020","volume":"51","text":"51(2020), 9, Seite e232-e237","issue":"9","extent":"6","pages":"e232-e237"},"language":["eng"],"note":["Gesehen am 29.06.04"],"pubHistory":["1.1970 -"]}],"id":{"eki":["1737351277"],"doi":["10.1161/STROKEAHA.120.029629"]},"physDesc":[{"extent":"6 S."}],"title":[{"title":"Primary multivessel occlusions treated with mechanical thrombectomy","title_sort":"Primary multivessel occlusions treated with mechanical thrombectomy"}],"type":{"bibl":"article-journal","media":"Online-Ressource"}} | ||
| SRT | |a KAESMACHERPRIMARYMUL1320 | ||