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Impaired retrograde transport by the Dynein/Dynactin complex contributes to Tau-induced toxicity

Abstract. The gene mapt codes for the microtubule-associated protein Tau. The R406W amino acid substitution in Tau is associated with frontotemporal dementia w

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Main Authors: Butzlaff, Malte (Author) , Hannan, Shabab B. (Author) , Karsten, Peter (Author) , Lenz, Sarah (Author) , Ng, Josephine (Author) , Voßfeldt, Hannes (Author) , Prüßing, Katja (Author) , Pflanz, Ralf (Author) , Schulz, Jörg B. (Author) , Rasse, Tobias M. (Author) , Voigt, Aaron (Author)
Format: Article (Journal)
Language:English
Published: 20 March 2015
In: Human molecular genetics
Year: 2015, Volume: 24, Issue: 13, Pages: 3623-3637
ISSN:1460-2083
DOI:10.1093/hmg/ddv107
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1093/hmg/ddv107
Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/hmg/article/24/13/3623/610570
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Author Notes:Malte Butzlaff, Shabab B. Hannan, Peter Karsten, Sarah Lenz, Josephine Ng, Hannes Voßfeldt, Katja Prüßing, Ralf Pflanz, Jörg B. Schulz, Tobias Rasse and Aaron Voigt

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