ADAR-deficiency perturbs the global splicing landscape in mouse tissues

Adenosine-to-inosine RNA editing and pre-mRNA splicing largely occur cotranscriptionally and influence each other. Here, we use mice deficient in either one of the two editing enzymes ADAR (ADAR1) or ADARB1 (ADAR2) to determine the transcriptome-wide impact of RNA editing on splicing across differen...

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Main Authors: Kapoor, Utkarsh (Author) , Jakobi, Tobias (Author) , Dieterich, Christoph (Author)
Format: Article (Journal)
Language:English
Published: July 29, 2020
In: Genome research
Year: 2020, Volume: 30, Issue: 8, Pages: 1107-1118
ISSN:1549-5469
DOI:10.1101/gr.256933.119
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1101/gr.256933.119
Verlag, lizenzpflichtig, Volltext: http://genome.cshlp.org/content/30/8/1107
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Author Notes:Utkarsh Kapoor, Konstantin Licht, Fabian Amman, Tobias Jakobi, David Martin, Christoph Dieterich, and Michael F. Jantsch

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