Understanding angiodiversity: insights from single cell biology
Skip to Next Section - Blood vessels have long been considered as passive conduits for delivering blood. However, in recent years, cells of the vessel wall (endothelial cells, smooth muscle cells and pericytes) have emerged as active, highly dynamic components that orchestrate crosstalk between the...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
12 August 2020
|
| In: |
Development
Year: 2020, Jahrgang: 147, Heft: 15 |
| ISSN: | 1477-9129 |
| DOI: | 10.1242/dev.146621 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1242/dev.146621 Verlag, lizenzpflichtig, Volltext: https://dev.biologists.org/content/147/15/dev146621 
|
| Verfasserangaben: | Moritz Jakab and Hellmut G. Augustin |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 173802153X | ||
| 003 | DE-627 | ||
| 005 | 20220819013955.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 201105s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1242/dev.146621 |2 doi | |
| 035 | |a (DE-627)173802153X | ||
| 035 | |a (DE-599)KXP173802153X | ||
| 035 | |a (OCoLC)1341375546 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Jakab, Moritz |d 1991- |e VerfasserIn |0 (DE-588)1220893331 |0 (DE-627)1738021564 |4 aut | |
| 245 | 1 | 0 | |a Understanding angiodiversity |b insights from single cell biology |c Moritz Jakab and Hellmut G. Augustin |
| 264 | 1 | |c 12 August 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 05.11.2020 | ||
| 520 | |a Skip to Next Section - Blood vessels have long been considered as passive conduits for delivering blood. However, in recent years, cells of the vessel wall (endothelial cells, smooth muscle cells and pericytes) have emerged as active, highly dynamic components that orchestrate crosstalk between the circulation and organs. Encompassing the whole body and being specialized to the needs of distinct organs, it is not surprising that vessel lining cells come in different flavours. There is calibre-specific specialization (arteries, arterioles, capillaries, venules, veins), but also organ-specific heterogeneity in different microvascular beds (continuous, discontinuous, sinusoidal). Recent technical advances in the field of single cell biology have enabled the profiling of thousands of single cells and, hence, have allowed for the molecular dissection of such angiodiversity, yielding a hitherto unparalleled level of spatial and functional resolution. Here, we review how these approaches have contributed to our understanding of angiodiversity. | ||
| 700 | 1 | |a Augustin, Hellmut |d 1959- |e VerfasserIn |0 (DE-588)102307737X |0 (DE-627)717361470 |0 (DE-576)171124766 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Development |d Cambridge : The Company of Biologists, 1987 |g 147(2020,15) Artikel-Nummer dev146621, 13 Seiten |h Online-Ressource |w (DE-627)31982439X |w (DE-600)2007916-3 |w (DE-576)090893131 |x 1477-9129 |7 nnas |a Understanding angiodiversity insights from single cell biology |
| 773 | 1 | 8 | |g volume:147 |g year:2020 |g number:15 |a Understanding angiodiversity insights from single cell biology |
| 856 | 4 | 0 | |u https://doi.org/10.1242/dev.146621 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://dev.biologists.org/content/147/15/dev146621 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20201105 | ||
| 993 | |a Article | ||
| 994 | |a 2020 | ||
| 998 | |g 102307737X |a Augustin, Hellmut |m 102307737X:Augustin, Hellmut |d 50000 |d 60000 |d 65000 |e 50000PA102307737X |e 60000PA102307737X |e 65000PA102307737X |k 0/50000/ |k 0/60000/ |k 1/60000/65000/ |p 2 |y j | ||
| 998 | |g 1220893331 |a Jakab, Moritz |m 1220893331:Jakab, Moritz |d 60000 |d 65000 |e 60000PJ1220893331 |e 65000PJ1220893331 |k 0/60000/ |k 1/60000/65000/ |p 1 |x j | ||
| 999 | |a KXP-PPN173802153X |e 3792781999 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"given":"Moritz","family":"Jakab","role":"aut","roleDisplay":"VerfasserIn","display":"Jakab, Moritz"},{"role":"aut","display":"Augustin, Hellmut","roleDisplay":"VerfasserIn","given":"Hellmut","family":"Augustin"}],"name":{"displayForm":["Moritz Jakab and Hellmut G. Augustin"]},"title":[{"title_sort":"Understanding angiodiversity","subtitle":"insights from single cell biology","title":"Understanding angiodiversity"}],"origin":[{"dateIssuedDisp":"12 August 2020","dateIssuedKey":"2020"}],"id":{"eki":["173802153X"],"doi":["10.1242/dev.146621"]},"note":["Gesehen am 05.11.2020"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"recId":"173802153X","relHost":[{"id":{"zdb":["2007916-3"],"eki":["31982439X"],"issn":["1477-9129"]},"origin":[{"dateIssuedKey":"1987","publisher":"The Company of Biologists","dateIssuedDisp":"1987-","publisherPlace":"Cambridge"}],"name":{"displayForm":["Company of Biologists"]},"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title_sort":"Development","title":"Development"}],"part":{"year":"2020","issue":"15","text":"147(2020,15) Artikel-Nummer dev146621, 13 Seiten","volume":"147"},"titleAlt":[{"title":"Development <Cambridge>"}],"pubHistory":["Volume 99, 1 (January 1987)-"],"language":["eng"],"corporate":[{"display":"The Company of Biologists","roleDisplay":"Herausgebendes Organ","role":"isb"}],"recId":"31982439X","disp":"Understanding angiodiversity insights from single cell biologyDevelopment","note":["Gesehen am 26.06.2025"],"type":{"media":"Online-Ressource","bibl":"periodical"}}],"language":["eng"]} | ||
| SRT | |a JAKABMORITUNDERSTAND1220 | ||