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Inhibition of overexpressed Kv3.4 augments HPV in endotoxemic mice

Hypoxic pulmonary vasoconstriction (HPV) is a reaction of the pulmonary vasculature upon hypoxia, diverting blood flow into ventilated areas to preserve oxygenation. It is impaired in endotoxemia or ARDS. Voltage gated potassium channels have been shown to play a key role in the regulation of HPV. T...

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Main Authors: Turzo, Maurizio (Author) , Metzger, Karin (Author) , Lasitschka, Felix (Author) , Weigand, Markus A. (Author) , Busch, Cornelius (Author)
Format: Article (Journal)
Language:English
Published: 08 October 2020
In: BMC pulmonary medicine
Year: 2020, Volume: 20
ISSN:1471-2466
DOI:10.1186/s12890-020-01278-5
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12890-020-01278-5
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Author Notes:Maurizio Turzo, Karin Metzger, Felix Lasitschka, Markus A. Weigand and Cornelius J. Busch

MARC

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