Risk-seeking for losses is associated with 5-HTTLPR, but not with transient changes in 5-HT levels

Serotonin (5-HT) plays a key role in different aspects of value-based decision-making. A recent framework proposed that tonic 5-HT (together with dopamine, DA) codes future average reward expectations, providing a baseline against which possible choice outcomes are compared to guide decision-making.

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Bibliographic Details
Main Authors: Neukam, Philipp T. (Author) , Rietschel, Marcella (Author) , Witt, Stephanie (Author)
Format: Article (Journal)
Language:English
Published: 5 May 2018
In: Psychopharmacology
Year: 2018, Volume: 235, Issue: 7, Pages: 2151-2165
ISSN:1432-2072
DOI:10.1007/s00213-018-4913-9
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00213-018-4913-9
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Author Notes:Philipp T. Neukam, Nils B. Kroemer, Yacila I. Deza Araujo, Lydia Hellrung, Shakoor Pooseh, Marcella Rietschel, Stephanie H. Witt, Uwe Schwarzenbolz, Thomas Henle, Michael N. Smolka
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Summary:Serotonin (5-HT) plays a key role in different aspects of value-based decision-making. A recent framework proposed that tonic 5-HT (together with dopamine, DA) codes future average reward expectations, providing a baseline against which possible choice outcomes are compared to guide decision-making.
Item Description:Gesehen am 19.11.2020
Physical Description:Online Resource
ISSN:1432-2072
DOI:10.1007/s00213-018-4913-9