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Antibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) in cerebellar ataxia

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We report on a serum autoantibody associated with cerebellar ataxia. Immunohistochemical studies of sera from four patients referred for autoantibody testing revealed binding of high-titer (up to 1:5,000) IgG antibodies, mainly IgG1, to the molecular layer, Purkinje cell layer, and white matter on m...

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Main Authors: Jarius, Sven (Author) , Scharf, Madeleine (Author) , Begemann, Nora (Author) , Stöcker, Winfried (Author) , Probst, Christian (Author) , Serysheva, Irina I. (Author) , Nagel, Sigrun (Author) , Graus, Francesc (Author) , Psimaras, Dimitri (Author) , Wildemann, Brigitte (Author) , Komorowski, Lars (Author)
Format: Article (Journal)
Language:English
Published: 11 December 2014
In: Journal of neuroinflammation
Year: 2014, Volume: 11
ISSN:1742-2094
DOI:10.1186/s12974-014-0206-3
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12974-014-0206-3
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Author Notes:Sven Jarius, Madeleine Scharf, Nora Begemann, Winfried Stöcker, Christian Probst, Irina I. Serysheva, Sigrun Nagel, Francesc Graus, Dimitri Psimaras, Brigitte Wildemann and Lars Komorowski
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Antibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) in cerebellar ataxia by Jarius, Sven (Author) , Wildemann, Brigitte (Author) ,

BioMed Central 2014

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