In vivo vaccination with cell line-derived whole tumor lysates: neoantigen quality, not quantity matters
Cancer vaccines provide a complex source of neoantigens. Still, increasing evidence reveals that the neoantigen quality rather than the quantity is predictive for treatment outcome.
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| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
21 October 2020
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| In: |
Journal of translational medicine
Year: 2020, Jahrgang: 18, Pages: 1-15 |
| ISSN: | 1479-5876 |
| DOI: | 10.1186/s12967-020-02570-y |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12967-020-02570-y |
| Verfasserangaben: | Inken Salewski, Yvonne Saara Gladbach, Steffen Kuntoff, Nina Irmscher, Olga Hahn, Christian Junghanss and Claudia Maletzki |
| Zusammenfassung: | Cancer vaccines provide a complex source of neoantigens. Still, increasing evidence reveals that the neoantigen quality rather than the quantity is predictive for treatment outcome. |
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| Beschreibung: | Gesehen am 30.11.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1479-5876 |
| DOI: | 10.1186/s12967-020-02570-y |