Premature ovarian failure
The prevalence of a premature ovarian failure (POF) is about 1 % of all fertile women. The etiology of the disease is heterogenic and in most cases unknown. Patients history and determination of serum FSH (continously above 40 IE/l) is important. Concomitant diseases such as autoimmune diseases or a...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
01 October 1999
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| In: |
Reproduktionsmedizin
Year: 1999, Volume: 15, Issue: 5, Pages: 343-347 |
| ISSN: | 1434-808X |
| DOI: | 10.1007/s004440050124 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s004440050124 Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s004440050124 
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| Author Notes: | B. Runnebaum, T. Rabe |
| Summary: | The prevalence of a premature ovarian failure (POF) is about 1 % of all fertile women. The etiology of the disease is heterogenic and in most cases unknown. Patients history and determination of serum FSH (continously above 40 IE/l) is important. Concomitant diseases such as autoimmune diseases or a galactosemia must be excluded. Fertility cannot be improved by suppression of serum FSH by means of GnRH-analogues or Danazol followed by a high dose stimulation with gonadotropins or a pretreatment with estrogens. The prognosis in view to a pregnancy is unfavourable and in the individual case not predictable. A long term hormone replacement therapy is absolutely required in view to the health of the women with POF. In patients treated with biphasic HRT regimen a spontanous pregnancy cannot be excluded. |
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| Item Description: | Es besteht kein Link zum Volltext des Artikels Gesehen am 01.12.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1434-808X |
| DOI: | 10.1007/s004440050124 |