Hypothetical proteins as predecessors of long non-coding RNAs

Hypothetical Proteins [HP] are the transcripts predicted to be expressed in an organism, but no evidence of it exists in gene banks. On the other hand, long non-coding RNAs [lncRNAs] are the transcripts that might he present in the 5' UTR or intergenic regions of the genes whose lengths are abo...

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Main Authors: Malik, Girik (Author) , Agarwal, Tanu (Author) , Raj, Utkarsh (Author) , Sundararajan, Vijayaraghava Seshadri (Author) , Bandapalli, Obul Reddy (Author) , Suravajhala, Prashanth (Author)
Format: Article (Journal)
Language:English
Published: 2020
In: Current genomics
Year: 2020, Volume: 21, Issue: 7, Pages: 531-535
ISSN:1875-5488
DOI:10.2174/1389202921999200611155418
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.2174/1389202921999200611155418
Verlag, lizenzpflichtig, Volltext: https://www.eurekaselect.com/182728/article
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Author Notes:Girik Malik, Tanu Agarwal, Utkarsh Raj, Vijayaraghava Seshadri Sundararajan, Obul Reddy Bandapalli, Prashanth Suravajhala
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Summary:Hypothetical Proteins [HP] are the transcripts predicted to be expressed in an organism, but no evidence of it exists in gene banks. On the other hand, long non-coding RNAs [lncRNAs] are the transcripts that might he present in the 5' UTR or intergenic regions of the genes whose lengths are above 200 bases. With the known unknown [KU] regions in the genomes rapidly existing in gene banks, there is a need to understand the role of open reading frames in the context of annotation. In this commentary, we emphasize that HPs could indeed he the predecessors of lncRNAs.
Item Description:Gesehen am 03.12.2020
Physical Description:Online Resource
ISSN:1875-5488
DOI:10.2174/1389202921999200611155418