Hypothetical proteins as predecessors of long non-coding RNAs

Hypothetical Proteins [HP] are the transcripts predicted to be expressed in an organism, but no evidence of it exists in gene banks. On the other hand, long non-coding RNAs [lncRNAs] are the transcripts that might he present in the 5' UTR or intergenic regions of the genes whose lengths are abo...

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Hauptverfasser: Malik, Girik (VerfasserIn) , Agarwal, Tanu (VerfasserIn) , Raj, Utkarsh (VerfasserIn) , Sundararajan, Vijayaraghava Seshadri (VerfasserIn) , Bandapalli, Obul Reddy (VerfasserIn) , Suravajhala, Prashanth (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2020
In: Current genomics
Year: 2020, Jahrgang: 21, Heft: 7, Pages: 531-535
ISSN:1875-5488
DOI:10.2174/1389202921999200611155418
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.2174/1389202921999200611155418
Verlag, lizenzpflichtig, Volltext: https://www.eurekaselect.com/182728/article
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Verfasserangaben:Girik Malik, Tanu Agarwal, Utkarsh Raj, Vijayaraghava Seshadri Sundararajan, Obul Reddy Bandapalli, Prashanth Suravajhala

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520 |a Hypothetical Proteins [HP] are the transcripts predicted to be expressed in an organism, but no evidence of it exists in gene banks. On the other hand, long non-coding RNAs [lncRNAs] are the transcripts that might he present in the 5' UTR or intergenic regions of the genes whose lengths are above 200 bases. With the known unknown [KU] regions in the genomes rapidly existing in gene banks, there is a need to understand the role of open reading frames in the context of annotation. In this commentary, we emphasize that HPs could indeed he the predecessors of lncRNAs. 
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