Cilengitide affects tumor compartment, vascularization and microenvironment in experimental bone metastases as shown by longitudinal 18F-FDG PET and gene expression analysis
Aim of this study was to investigate the specific treatment effects of inhibiting αvβ3/αvβ5 integrins by cilengitide in an animal model of breast cancer bone metastases using dynamic 18F-FDG PET and gene expression analysis.
Gespeichert in:
| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2013
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| In: |
Journal of cancer research and clinical oncology
Year: 2012, Jahrgang: 139, Heft: 4, Pages: 573-583 |
| ISSN: | 1432-1335 |
| DOI: | 10.1007/s00432-012-1360-6 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00432-012-1360-6
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| Verfasserangaben: | Maren Bretschi, Caixia Cheng, Hendrik Witt, Antonia Dimitrakopoulou-Strauss, Ludwig G. Strauss, Wolfhard Semmler, Tobias Bäuerle |
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| 520 | |a Aim of this study was to investigate the specific treatment effects of inhibiting αvβ3/αvβ5 integrins by cilengitide in an animal model of breast cancer bone metastases using dynamic 18F-FDG PET and gene expression analysis. | ||
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