Cilengitide affects tumor compartment, vascularization and microenvironment in experimental bone metastases as shown by longitudinal 18F-FDG PET and gene expression analysis

Aim of this study was to investigate the specific treatment effects of inhibiting αvβ3/αvβ5 integrins by cilengitide in an animal model of breast cancer bone metastases using dynamic 18F-FDG PET and gene expression analysis.

Saved in:

Bibliographic Details
Main Authors:	Bretschi, Maren (Author) , Cheng, Caixia (Author) , Witt, Hendrik (Author) , Dimitrakopoulou-Strauss, Antonia (Author) , Strauss, Ludwig G. (Author) , Semmler, Wolfhard (Author) , Bäuerle, Tobias (Author)
Format:	Article (Journal)
Language:	English
Published:	2013
In:	Journal of cancer research and clinical oncology Year: 2012, Volume: 139, Issue: 4, Pages: 573-583
ISSN:	1432-1335
DOI:	10.1007/s00432-012-1360-6
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00432-012-1360-6
Author Notes:	Maren Bretschi, Caixia Cheng, Hendrik Witt, Antonia Dimitrakopoulou-Strauss, Ludwig G. Strauss, Wolfhard Semmler, Tobias Bäuerle

Description
Summary:	Aim of this study was to investigate the specific treatment effects of inhibiting αvβ3/αvβ5 integrins by cilengitide in an animal model of breast cancer bone metastases using dynamic 18F-FDG PET and gene expression analysis.
Item Description:	Im Titel ist "18" in 18F-FDG PET hochgestellt Published online: 11 December 2012 Gesehen am 04.12.2020
Physical Description:	Online Resource
ISSN:	1432-1335
DOI:	10.1007/s00432-012-1360-6