Gemcitabine as adjuvant chemotherapy in patients with high-risk early breast cancer: results from the randomized phase III SUCCESS-A trial

When chemotherapy is indicated in patients with early breast cancer, regimens that contain anthracyclines and taxanes are established standard treatments. Gemcitabine has shown promising effects on the response and prognosis in patients with metastatic breast cancer. The SUCCESS-A trial (NCT02181101...

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Main Authors: De Gregorio, Amelie (Author) , Häberle, Lothar (Author) , Fasching, Peter A. (Author) , Müller, Volkmar (Author) , Schrader, Iris (Author) , Lorenz, Ralf (Author) , Forstbauer, Helmut (Author) , Friedl, Thomas W. P. (Author) , Bauer, Emanuel (Author) , de Gregorio, Nikolaus (Author) , Deniz, Miriam (Author) , Fink, Visnja (Author) , Bekes, Inga (Author) , Andergassen, Ulrich (Author) , Schneeweiss, Andreas (Author) , Tesch, Hans (Author) , Mahner, Sven (Author) , Brucker, Sara Y. (Author) , Blohmer, Jens-Uwe (Author) , Fehm, Tanja (Author) , Heinrich, Georg (Author) , Lato, Krisztian (Author) , Beckmann, Matthias W. (Author) , Rack, Brigitte (Author) , Janni, Wolfgang (Author)
Format: Article (Journal)
Language:English
Published: 23 October 2020
In: Breast cancer research
Year: 2020, Volume: 22, Pages: 1-11
ISSN:1465-542X
DOI:10.1186/s13058-020-01348-w
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13058-020-01348-w
Verlag, lizenzpflichtig, Volltext: https://breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-020-01348-w
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Author Notes:Amelie de Gregorio, Lothar Häberle, Peter A. Fasching, Volkmar Müller, Iris Schrader, Ralf Lorenz, Helmut Forstbauer, Thomas W.P. Friedl, Emanuel Bauer, Nikolaus de Gregorio, Miriam Deniz, Visnja Fink, Inga Bekes, Ulrich Andergassen, Andreas Schneeweiss, Hans Tesch, Sven Mahner, Sara Y. Brucker, Jens-Uwe Blohmer, Tanja N. Fehm, Georg Heinrich, Krisztian Lato, Matthias W. Beckmann, Brigitte Rack and Wolfgang Janni
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Summary:When chemotherapy is indicated in patients with early breast cancer, regimens that contain anthracyclines and taxanes are established standard treatments. Gemcitabine has shown promising effects on the response and prognosis in patients with metastatic breast cancer. The SUCCESS-A trial (NCT02181101) examined the addition of gemcitabine to a standard chemotherapy regimen in high-risk early breast cancer patients.
Item Description:Gesehen am 08.12.2020
Physical Description:Online Resource
ISSN:1465-542X
DOI:10.1186/s13058-020-01348-w