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Immunogenicity of constitutively active V599EBRaf

Activating BRAF somatic missense mutations within the kinase domain are present in 60-66% of melanomas. The vast majority of these represent a single substitution of glutamate for valine (V599E). Here, we demonstrate spontaneous HLA-B*2705-restricted cytotoxic T-cell responses against an epitope der...

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Hauptverfasser: Andersen, Mads Hald (VerfasserIn) , Ugurel, Selma (VerfasserIn) , Schadendorf, Dirk (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: August 2, 2004
In: Cancer research
Year: 2004, Jahrgang: 64, Heft: 15, Pages: 5456-5460
ISSN:1538-7445
DOI:10.1158/0008-5472.CAN-04-0937
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1158/0008-5472.CAN-04-0937
Verlag, lizenzpflichtig, Volltext: https://cancerres.aacrjournals.org/content/64/15/5456
Volltext
Verfasserangaben:Mads Hald Andersen, Joachim Fensterle, Selma Ugurel, Sine Reker, Roland Houben, Per Guldberg, Thomas G. Berger, Dirk Schadendorf, Uwe Trefzer, Eva-B. Bröcker, Per thor Straten, Ulf R. Rapp, and Jürgen C. Becker

MARC

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