Enantioselective iron-catalyzed azidation of β-keto esters and oxindoles
The first example of Fe-catalyzed enantioselective azidations of β-keto esters and oxindoles using a readily available N3-transfer reagent is reported. A number of α-azido-β-keto esters were obtained with up to 93% ee, and this methodology also generates 3-substitued 3-azidooxindoles with high enant...
Gespeichert in:
| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
March 28, 2013
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| In: |
Journal of the American Chemical Society
Year: 2013, Jahrgang: 135, Heft: 14, Pages: 5356-5359 |
| ISSN: | 1520-5126 |
| DOI: | 10.1021/ja402082p |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1021/ja402082p |
| Verfasserangaben: | Qing-Hai Deng, Tim Bleith, Hubert Wadepohl, and Lutz H. Gade |
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| 520 | |a The first example of Fe-catalyzed enantioselective azidations of β-keto esters and oxindoles using a readily available N3-transfer reagent is reported. A number of α-azido-β-keto esters were obtained with up to 93% ee, and this methodology also generates 3-substitued 3-azidooxindoles with high enantioselectivities (up to 94%). | ||
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