Benzo[a]pyrene enhances lipid peroxidation induced DNA damage in aorta of apolipoprotein E knockout mice

The genotoxic compound benzo[a]pyrene (B[a]P) enhances atherosclerotic plaque progression, possibly by inducing oxidative stress and subsequent lipid peroxidation (LPO). Since LPO plays a key role in atherosclerosis, stable LPO derived DNA modifications such as 1,N6-ethenodeoxyadenosine (εdA) and 3,...

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Bibliographic Details
Main Authors:	Godschalk, Roger (Author) , Bartsch, Helmut (Author) , Nair, Jagadeesan (Author)
Format:	Article (Journal)
Language:	English
Published:	07 Jul 2009
In:	Free radical research Year: 2003, Volume: 37, Issue: 12, Pages: 1299-1305
ISSN:	1029-2470
DOI:	10.1080/10715760310001621333
Online Access:	Verlag, Volltext: https://doi.org/10.1080/10715760310001621333
Author Notes:	Roger Godschalk, Daniëlle Curfs, Helmut Bartsch, Frederik-Jan Van Schooten & Jagadeesan Nair

CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation by Alexandrov, Kroum (Author) , Bartsch, Helmut (Author) ,

in: Carcinogenesis, 23 (2002), 12, Seite 1969-1977

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Benzo[a]pyrene enhances lipid peroxidation induced DNA damage in aorta of apolipoprotein E knockout mice

CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation by Alexandrov, Kroum (Author) , Bartsch, Helmut (Author) ,

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