Coupling of NMDA receptors and TRPM4 guides discovery of unconventional neuroprotectants
Interface targeting skirts excitotoxicity - Nearly all attempts to use traditional N-methyl-d-aspartate receptor (NMDAR) antagonists to treat neurodegenerative diseases have failed. This is because NMDARs are not only promoters of neuronal death but also have essential physiological roles in synapti...
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) Kapitel/Artikel |
| Sprache: | Englisch |
| Veröffentlicht: |
09 Oct 2020
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| In: |
Science. First release
Year: 2020, Jahrgang: 370, Pages: 1-9 |
| DOI: | 10.1126/science.aay3302 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1126/science.aay3302 Verlag, lizenzpflichtig, Volltext: https://science.sciencemag.org/content/370/6513/eaay3302 |
| Verfasserangaben: | Jing Yan, C. Peter Bengtson, Bettina Buchthal, Anna M. Hagenston, Hilmar Bading |
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