Extraction of respiratory myogram interference from the ECG and its application to characterize sleep-related breathing disorders in atrial fibrillation

BACKGROUND AND PURPOSE: Present methods to extract respiratory myogram interference (RMI) from the Holter-ECG and assess effect of supraventricular arrhythmias (SVAs) onto ECG-based detection of sleep-related breathing disorders (SRBDs) and AHI estimation. - METHODS: RMI was quantified as residual e...

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Hauptverfasser: Maier, Christoph (VerfasserIn) , Dickhaus, Hartmut (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2 August 2014
In: Journal of electrocardiology
Year: 2014, Jahrgang: 47, Heft: 6, Pages: 826-830
ISSN:1532-8430
DOI:10.1016/j.jelectrocard.2014.07.017
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.jelectrocard.2014.07.017
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Verfasserangaben:Christoph Maier, Hartmut Dickhaus

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520 |a BACKGROUND AND PURPOSE: Present methods to extract respiratory myogram interference (RMI) from the Holter-ECG and assess effect of supraventricular arrhythmias (SVAs) onto ECG-based detection of sleep-related breathing disorders (SRBDs) and AHI estimation. - METHODS: RMI was quantified as residual energy after ECG cancellation or high-pass filtering for different windowing constellations. In 140 cases without (SET_A) and 10 cases with persistent SVAs (SET_B), respiratory polysomnogram annotations served as reference for SRDB detection from Holter-ECGs. We applied our previously published method to identify SRDBs in 1-min epochs and estimate the AHI based on joint modulations in RMI and QRS-area. - RESULTS: Sensitivity and specificity of 0.855/0.860 in SET_A dropped to 0.831/0.75 in SET_B. A significantly higher number of wake events in SET_B likely contribute to the asymmetric decrease and is consistent with a tendency to overestimate the AHI. - CONCLUSIONS: Despite reduced accuracy, RMI and QRS-area appear relatively robust against SVA and promise Holter-based detection at least of medium to severe SRBDs also in patients with SVAs. 
650 4 |a Aged 
650 4 |a Algorithms 
650 4 |a Artifacts 
650 4 |a Atrial fibrillation 
650 4 |a Atrial Fibrillation 
650 4 |a Diagnosis, Computer-Assisted 
650 4 |a ECG 
650 4 |a ECG-derived respiration 
650 4 |a Electrocardiography 
650 4 |a Female 
650 4 |a Humans 
650 4 |a Male 
650 4 |a Middle Aged 
650 4 |a Pattern Recognition, Automated 
650 4 |a QRS amplitude 
650 4 |a Reproducibility of Results 
650 4 |a Respiratory Mechanics 
650 4 |a Respiratory myogram interference 
650 4 |a Sensitivity and Specificity 
650 4 |a Sleep apnea 
650 4 |a Sleep Apnea Syndromes 
650 4 |a Sleep-related breathing disorders 
650 4 |a Supraventricular arrhythmia 
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