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Sequential hepatic and pulmonary resections for metastatic colorectal cancer

Background: Resection of pulmonary or hepatic colorectal metastases is associated with a 5-year survival rate of 25-40 per cent. This report analyses outcome following sequential resection of colorectal metastases to both organs. Methods: Seventeen patients with histologically confirmed colorectal a...

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Hauptverfasser: Lehnert, Thomas (VerfasserIn) , Knaebel, Hanns-Peter (VerfasserIn) , Dueck, Margret (VerfasserIn) , Bülzebruck, Heinrich (VerfasserIn) , Herfarth, Christian (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 02 January 2003
In: The British journal of surgery
Year: 1999, Jahrgang: 86, Heft: 2, Pages: 241-243
ISSN:1365-2168
DOI:https://doi.org/10.1046/j.1365-2168.1999.01010.x
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/https://doi.org/10.1046/j.1365-2168.1999.01010.x
Verlag, lizenzpflichtig, Volltext: https://bjssjournals.onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2168.1999.01010.x
Volltext
Verfasserangaben:T. Lehnert, H.P. Knaebel, M. Dück, H. Bülzebruck, C. Herfarth
Beschreibung
Zusammenfassung:Background: Resection of pulmonary or hepatic colorectal metastases is associated with a 5-year survival rate of 25-40 per cent. This report analyses outcome following sequential resection of colorectal metastases to both organs. Methods: Seventeen patients with histologically confirmed colorectal adenocarcinoma and resection of liver and lung metastases were identified from a prospective database. Results: The median interval between resection of the primary tumour and first metastasis was 21 (range 0-64) months. The interval between resection of the first and subsequent metastases was 18 (range 1-74) months. No patient died in the postoperative period and there were two perioperative complications. The overall survival rate in 17 patients was 70 per cent at 2 years from resection of metastasis to the second organ, but the disease-free survival rate at 2 years was only 24 per cent. Conclusion: Although few long-term survivors were observed in this small series, sequential resection of hepatic and pulmonary metastases is warranted in a highly selected group of patients. © 1999 British Journal of Surgery Society Ltd
Beschreibung:First published: 02 January 2003
Gesehen am 28.12.2020
Beschreibung:Online Resource
ISSN:1365-2168
DOI:https://doi.org/10.1046/j.1365-2168.1999.01010.x

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