Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant
The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name sh...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
12 April 2013
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| In: |
Chromosome research
Year: 2013, Volume: 21, Issue: 2, Pages: 101-106 |
| ISSN: | 1573-6849 |
| DOI: | 10.1007/s10577-013-9347-y |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s10577-013-9347-y
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| Author Notes: | W.C. Earnshaw, S. Erhardt, und weitere 55 |
| Summary: | The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres. |
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| Item Description: | Gesehen am 07.01.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1573-6849 |
| DOI: | 10.1007/s10577-013-9347-y |