Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant
The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name sh...
Gespeichert in:
| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
12 April 2013
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| In: |
Chromosome research
Year: 2013, Jahrgang: 21, Heft: 2, Pages: 101-106 |
| ISSN: | 1573-6849 |
| DOI: | 10.1007/s10577-013-9347-y |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s10577-013-9347-y |
| Verfasserangaben: | W.C. Earnshaw, S. Erhardt, und weitere 55 |
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| 520 | |a The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres. | ||
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