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CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation

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Abstract. Benzo[ a ]pyrene diol epoxide (BPDE)-DNA adducts are involved in the induction of p53 mutations and probably in the causation of human lung cancer ass

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Bibliographic Details
Main Authors: Alexandrov, Kroum (Author) , Bartsch, Helmut (Author)
Format: Article (Journal)
Language:English
Published: 01 December 2002
In: Carcinogenesis
Year: 2002, Volume: 23, Issue: 12, Pages: 1969-1977
ISSN:1460-2180
DOI:10.1093/carcin/23.12.1969
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1093/carcin/23.12.1969
Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/carcin/article/23/12/1969/2608321
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Author Notes:Kroum Alexandrov, Ingolf Cascorbi, Margarita Rojas, Guy Bouvier, Erik Kriek and Helmut Bartsch
Description
Summary:Abstract. Benzo[ a ]pyrene diol epoxide (BPDE)-DNA adducts are involved in the induction of p53 mutations and probably in the causation of human lung cancer ass
Item Description:Gesehen am 12.01.2021
Physical Description:Online Resource
ISSN:1460-2180
DOI:10.1093/carcin/23.12.1969

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