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Reduced poly(ADP‐ribosyl)ation in lymphocytes of laryngeal cancer patients: Results of a case‐control study

Poly(ADP‐ribose) polymerase (PARP), a nuclear enzyme that is catalytically activated by DNA strand breaks, plays a complex role in DNA repair. Using NAD+ as a precursor, it catalyzes the formation of ADP‐ribose polymers, which are attached to various proteins.

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Bibliographische Detailangaben
Hauptverfasser: Rajaee-Behbahani, Nahid (VerfasserIn) , Schmezer, Peter (VerfasserIn) , Ramroth, Heribert (VerfasserIn) , Bartsch, Helmut (VerfasserIn) , Becher, Heiko (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 12 February 2002
In: International journal of cancer
Year: 2002, Jahrgang: 98, Heft: 5, Pages: 780-784
ISSN:1097-0215
DOI:10.1002/ijc.10234
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/ijc.10234
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/ijc.10234
Volltext
Verfasserangaben:Nahid Rajaee‐Behbahani, Peter Schmezer, Heribert Ramroth, Alexander Bürkle, Helmut Bartsch, Andreas Dietz and Heiko Becher
Beschreibung
Zusammenfassung:Poly(ADP‐ribose) polymerase (PARP), a nuclear enzyme that is catalytically activated by DNA strand breaks, plays a complex role in DNA repair. Using NAD+ as a precursor, it catalyzes the formation of ADP‐ribose polymers, which are attached to various proteins.
Beschreibung:Gesehen am 12.01.2021
DOI fehlerhaft
Beschreibung:Online Resource
ISSN:1097-0215
DOI:10.1002/ijc.10234

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