New concepts: growth hormone, insulin-like growth factor-I and the kidney
Both growth hormone (GH) and IGF-1 have major effects on normal kidney growth, structure and function and participate in the pathogenesis of certain kidney diseases. Furthermore when the kidneys fail there are profound changes in the circulating GH-IGF-1 system and the renal and systemic responses t...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
11 March 2004
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| In: |
Growth hormone & IGF research
Year: 2004, Volume: 14, Issue: 4, Pages: 270-276 |
| ISSN: | 1532-2238 |
| DOI: | 10.1016/j.ghir.2004.02.001 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ghir.2004.02.001 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S1096637404000243 
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| Author Notes: | Ralph Rabkin, Franz Schaefer |
MARC
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| 520 | |a Both growth hormone (GH) and IGF-1 have major effects on normal kidney growth, structure and function and participate in the pathogenesis of certain kidney diseases. Furthermore when the kidneys fail there are profound changes in the circulating GH-IGF-1 system and the renal and systemic responses to these hormones. In this brief review we address the advances that have been made in our understanding of the relationship between growth hormone GH and IGF-1 and the kidney in health and the systemic and local perturbations that occur in kidney disease and identify key unanswered questions. | ||
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