Peritoneal transport properties and dialysis dose affect growth and nutritional status in children on chronic peritoneal dialysis
Abstract. To evaluate a possible effect of peritoneal transport properties and dialysis dose on the physical development of children on chronic peritoneal dialysis, a cohort of 51 children was prospectively followed for 18 mo. Peritoneal transport characteristics were assessed by serial peritoneal e...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Körperschaft: | |
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
August 1, 1999
|
| In: |
Journal of the American Society of Nephrology
Year: 1999, Jahrgang: 10, Heft: 8, Pages: 1786-1792 |
| ISSN: | 1533-3450 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://jasn.asnjournals.org/content/10/8/1786
|
| Verfasserangaben: | Franz Schaefer, Günter Klaus, Otto Mehls, and The Mid-European Pediatric Peritoneal Dialysis Study Group (MEPPS) |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1744701970 | ||
| 003 | DE-627 | ||
| 005 | 20220819074733.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 210114s1999 xx |||||o 00| ||eng c | ||
| 035 | |a (DE-627)1744701970 | ||
| 035 | |a (DE-599)KXP1744701970 | ||
| 035 | |a (OCoLC)1341384998 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 110 | 2 | |a Mid-European Pediatric Peritoneal Dialysis Study Group (MEPPS) |e VerfasserIn |0 (DE-588)1225074061 |0 (DE-627)1744699291 |4 aut | |
| 245 | 1 | 0 | |a Peritoneal transport properties and dialysis dose affect growth and nutritional status in children on chronic peritoneal dialysis |c Franz Schaefer, Günter Klaus, Otto Mehls, and The Mid-European Pediatric Peritoneal Dialysis Study Group (MEPPS) |
| 264 | 1 | |c August 1, 1999 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 14.01.2021 | ||
| 520 | |a Abstract. To evaluate a possible effect of peritoneal transport properties and dialysis dose on the physical development of children on chronic peritoneal dialysis, a cohort of 51 children was prospectively followed for 18 mo. Peritoneal transport characteristics were assessed by serial peritoneal equilibration tests (PET), dialysis efficacy by dialysate and residual renal clearance measurements, and growth and nutritional status by the longitudinal changes (Δ) of height SD score (SDS), body mass index (BMI) SDS, and serum albumin. Δ height SDS was negatively correlated with the creatinine equilibration rate observed in the initial PET (r = -0.31, P < 0.05). Multiple regression analysis confirmed the negative effect of the high transporter state (partial r2 = 0.07), and disclosed an additional positive effect of dialytic CCr (partial r2 = 0.11) and a weak negative effect of daily dialysate volume (partial r2 = 0.04) on Δ height SDS. Δ BMI SDS was strongly age-dependent (r = -0.48, P < 0.001); while relative body mass gradually increased below 4 yr of age, it remained stable in older children. Positive changes in BMI SDS were associated with rapid PET creatinine equilibration rates (univariate r = 0.35, P < 0.05) and/or large dialysate volumes (multivariate partial r2 = 0.11), suggesting a role of dialytic glucose uptake in the development of obesity. The change in serum albumin concentrations was positively correlated with dialysate volume (partial r2 = 0.14), and negatively affected by dialytic protein losses (partial r2 = 0.06). In conclusion, the peritoneal transporter state is a weak but significant determinant of growth and body mass gain in children on chronic peritoneal dialysis. Rapid small solute equilibration contributes to impaired growth but enhanced acquisition of body mass. Dialytic small solute clearance has a weak positive effect on statural growth independent of the transporter state, but does not affect body mass gain. | ||
| 700 | 1 | |a Schaefer, Franz |d 1961- |e VerfasserIn |0 (DE-588)1023365383 |0 (DE-627)718365577 |0 (DE-576)366705598 |4 aut | |
| 700 | 1 | |a Klaus, Günter |e VerfasserIn |0 (DE-588)1106410408 |0 (DE-627)863131182 |0 (DE-576)474097021 |4 aut | |
| 700 | 1 | |a Mehls, Otto |e VerfasserIn |0 (DE-588)1111580413 |0 (DE-627)865658137 |0 (DE-576)476191424 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |a American Society of Nephrology |t Journal of the American Society of Nephrology |d Washington, DC : American Society of Nephrology, 1990 |g 10(1999), 8, Seite 1786-1792 |h Online-Ressource |w (DE-627)324616481 |w (DE-600)2029124-3 |w (DE-576)094113769 |x 1533-3450 |7 nnas |
| 773 | 1 | 8 | |g volume:10 |g year:1999 |g number:8 |g pages:1786-1792 |g extent:7 |a Peritoneal transport properties and dialysis dose affect growth and nutritional status in children on chronic peritoneal dialysis |
| 856 | 4 | 0 | |u https://jasn.asnjournals.org/content/10/8/1786 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20210114 | ||
| 993 | |a Article | ||
| 994 | |a 1999 | ||
| 998 | |g 1111580413 |a Mehls, Otto |m 1111580413:Mehls, Otto |d 910000 |d 910500 |e 910000PM1111580413 |e 910500PM1111580413 |k 0/910000/ |k 1/910000/910500/ |p 3 |y j | ||
| 998 | |g 1106410408 |a Klaus, Günter |m 1106410408:Klaus, Günter |d 50000 |e 50000PK1106410408 |k 0/50000/ |p 2 | ||
| 998 | |g 1023365383 |a Schaefer, Franz |m 1023365383:Schaefer, Franz |d 910000 |d 910500 |e 910000PS1023365383 |e 910500PS1023365383 |k 0/910000/ |k 1/910000/910500/ |p 1 |x j | ||
| 999 | |a KXP-PPN1744701970 |e 3836475707 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"given":"Franz","display":"Schaefer, Franz","family":"Schaefer","role":"aut"},{"display":"Klaus, Günter","family":"Klaus","role":"aut","given":"Günter"},{"given":"Otto","role":"aut","family":"Mehls","display":"Mehls, Otto"}],"note":["Gesehen am 14.01.2021"],"corporate":[{"display":"Mid-European Pediatric Peritoneal Dialysis Study Group (MEPPS)","role":"aut"}],"origin":[{"dateIssuedKey":"1999","dateIssuedDisp":"August 1, 1999"}],"id":{"eki":["1744701970"]},"title":[{"title_sort":"Peritoneal transport properties and dialysis dose affect growth and nutritional status in children on chronic peritoneal dialysis","title":"Peritoneal transport properties and dialysis dose affect growth and nutritional status in children on chronic peritoneal dialysis"}],"language":["eng"],"name":{"displayForm":["Franz Schaefer, Günter Klaus, Otto Mehls, and The Mid-European Pediatric Peritoneal Dialysis Study Group (MEPPS)"]},"recId":"1744701970","type":{"bibl":"article-journal","media":"Online-Ressource"},"physDesc":[{"extent":"7 S."}],"relHost":[{"id":{"zdb":["2029124-3"],"eki":["324616481"],"issn":["1533-3450"]},"disp":"American Society of NephrologyJournal of the American Society of Nephrology","origin":[{"publisher":"American Society of Nephrology ; Ovid","dateIssuedKey":"1990","publisherPlace":"Washington, DC ; [Erscheinungsort nicht ermittelbar]","dateIssuedDisp":"1990-"}],"corporate":[{"role":"aut","display":"American Society of Nephrology"}],"titleAlt":[{"title":"JASN"}],"pubHistory":["1.1990 -"],"note":["Gesehen am 19.08.24"],"title":[{"subtitle":"JASN","title_sort":"Journal of the American Society of Nephrology","title":"Journal of the American Society of Nephrology"}],"recId":"324616481","type":{"bibl":"periodical","media":"Online-Ressource"},"language":["eng"],"part":{"extent":"7","year":"1999","pages":"1786-1792","issue":"8","text":"10(1999), 8, Seite 1786-1792","volume":"10"},"physDesc":[{"extent":"Online-Ressource"}]}]} | ||
| SRT | |a MIDEUROPEAPERITONEAL1199 | ||