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Mechanisms of mitogen-activated protein kinase inhibition by parathyroid hormone in osteoblast-like cells

Parathyroid hormone (PTH) dose dependently inhibits growth factor- and stress-induced osteoblast proliferation via inactivating mitogen-activated protein kinase (MAPK) signaling pathways. Osteoblasts have recently been shown to express MAPK phosphatase (MKP)-1, a dual-specific phosphatase inactivato...

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Main Authors: Hömme, Meike (Author) , Schmitt, Claus P. (Author) , Mehls, Otto (Author) , Schaefer, Franz (Author)
Format: Article (Journal)
Language:English
Published: October 25, 2004
In: Journal of the American Society of Nephrology
Year: 2004, Volume: 15, Issue: 11, Pages: 2844-2850
ISSN:1533-3450
DOI:10.1097/01.ASN.0000143472.13214.2C
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1097/01.ASN.0000143472.13214.2C
Verlag, lizenzpflichtig, Volltext: https://jasn.asnjournals.org/content/15/11/2844
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Author Notes:Meike Hömme, Claus P. Schmitt, Otto Mehls, and Franz Schaefer

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