Fundamental properties of unperturbed haematopoiesis from stem cells in vivo
Inducible genetic labelling of haematopoietic stem cells (HSCs) and linked mathematical modelling show that at least 30% of all HSCs are productive, and that adult haematopoiesis is largely sustained by ‘short-term’ downstream stem cells that operate near self-renewal in the steady state; HSC fate m...
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| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
11 February 2015
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| In: |
Nature
Year: 2015, Jahrgang: 518, Heft: 7540, Pages: 542-546 |
| ISSN: | 1476-4687 |
| DOI: | 10.1038/nature14242 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nature14242 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nature14242 
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| Verfasserangaben: | Katrin Busch, Kay Klapproth, Melania Barile, Michael Flossdorf, Tim Holland-Letz, Susan M. Schlenner, Michael Reth, Thomas Höfer, Hans-Reimer Rodewald |
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