Sympathetic efferent neurons are less sensitive than nociceptors to 4 Hz sinusoidal stimulation

Background - Sinusoidal current stimuli preferentially activate C‐nociceptors. Sodium channel isoforms NaV1.7 and NaV1.8 have been implicated in this. Sympathetic efferent neurons lack NaV1.8 and were explored upon sinusoidal activation.

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Bibliographic Details
Main Authors: Jonas, Robin (Author) , Namer, Barbara (Author) , Schnakenberg, Mark (Author) , Soares, Sabrina (Author) , Pakalniškis, Julius (Author) , Carr, Richard (Author) , Schmelz, Martin (Author) , Rukwied, Roman (Author)
Format: Article (Journal)
Language:English
Published: 2020
In: European journal of pain
Year: 2020, Volume: 24, Issue: 1, Pages: 122-133
ISSN:1532-2149
DOI:10.1002/ejp.1467
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/ejp.1467
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/ejp.1467
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Author Notes:Robin Jonas, Barbara Namer, Mark Schnakenberg, Sabrina Soares, Julius Pakalniskis, Richard Carr, Martin Schmelz, Roman Rukwied
Description
Summary:Background - Sinusoidal current stimuli preferentially activate C‐nociceptors. Sodium channel isoforms NaV1.7 and NaV1.8 have been implicated in this. Sympathetic efferent neurons lack NaV1.8 and were explored upon sinusoidal activation.
Item Description:First published: 08 August 2019
Gesehen am 19.01.2021
Physical Description:Online Resource
ISSN:1532-2149
DOI:10.1002/ejp.1467