Sympathetic efferent neurons are less sensitive than nociceptors to 4 Hz sinusoidal stimulation
Background - Sinusoidal current stimuli preferentially activate C‐nociceptors. Sodium channel isoforms NaV1.7 and NaV1.8 have been implicated in this. Sympathetic efferent neurons lack NaV1.8 and were explored upon sinusoidal activation.
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| Main Authors: | , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2020
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| In: |
European journal of pain
Year: 2020, Volume: 24, Issue: 1, Pages: 122-133 |
| ISSN: | 1532-2149 |
| DOI: | 10.1002/ejp.1467 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/ejp.1467 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/ejp.1467 |
| Author Notes: | Robin Jonas, Barbara Namer, Mark Schnakenberg, Sabrina Soares, Julius Pakalniskis, Richard Carr, Martin Schmelz, Roman Rukwied |
| Summary: | Background - Sinusoidal current stimuli preferentially activate C‐nociceptors. Sodium channel isoforms NaV1.7 and NaV1.8 have been implicated in this. Sympathetic efferent neurons lack NaV1.8 and were explored upon sinusoidal activation. |
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| Item Description: | First published: 08 August 2019 Gesehen am 19.01.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1532-2149 |
| DOI: | 10.1002/ejp.1467 |