Vasodilation of rat skeletal muscle arteries by the novel BK channel opener GoSlo is mediated by the simultaneous activation of BK and Kv7 channels
Background and Purpose - BK channels play important roles in various physiological and pathophysiological processes and thus have been the target of several drug development programmes focused on creating new efficacious BK channel openers, such as the GoSlo‐SR compounds.
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2020
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| In: |
British journal of pharmacology
Year: 2020, Volume: 177, Issue: 5, Pages: 1164-1186 |
| ISSN: | 1476-5381 |
| DOI: | 10.1111/bph.14910 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1111/bph.14910 Verlag, lizenzpflichtig, Volltext: https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14910 |
| Author Notes: | Olga Zavaritskaya, Srikanth Dudem, Dongyu Ma, Kaneez E. Rabab, Sarah Albrecht, Dmitry Tsvetkov, Mario Kassmann, Keith Thornbury, Mitko Mladenov, Claire Kammermeier, Gerard Sergeant, Nicholas Mullins, Ornella Wouappi, Hannah Wurm, Aimo Kannt, Maik Gollasch, Mark A. Hollywood, Rudolf Schubert |
| Summary: | Background and Purpose - BK channels play important roles in various physiological and pathophysiological processes and thus have been the target of several drug development programmes focused on creating new efficacious BK channel openers, such as the GoSlo‐SR compounds. |
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| Item Description: | First published: 28 October 2019 Im Titel ist "v" bei "Kv7" tiefgestellt Gesehen am 20.01.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1476-5381 |
| DOI: | 10.1111/bph.14910 |