Vasodilation of rat skeletal muscle arteries by the novel BK channel opener GoSlo is mediated by the simultaneous activation of BK and Kv7 channels

Background and Purpose - BK channels play important roles in various physiological and pathophysiological processes and thus have been the target of several drug development programmes focused on creating new efficacious BK channel openers, such as the GoSlo‐SR compounds.

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Bibliographic Details
Main Authors: Zavaritskaya, Olga (Author) , Dudem, Srikanth (Author) , Ma, Dongyu (Author) , Rabab, Kaneez E. (Author) , Albrecht, Sarah (Author) , Tsvetkov, Dmitry (Author) , Kassmann, Mario (Author) , Thornbury, Keith (Author) , Mladenov, Mitko (Author) , Kammermeier, Claire (Author) , Sergeant, Gerard (Author) , Mullins, Nicholas (Author) , Wouappi, Ornella (Author) , Wurm, Hannah (Author) , Kannt, Aimo (Author) , Gollasch, Maik (Author) , Hollywood, Mark A. (Author) , Schubert, Rudolf (Author)
Format: Article (Journal)
Language:English
Published: 2020
In: British journal of pharmacology
Year: 2020, Volume: 177, Issue: 5, Pages: 1164-1186
ISSN:1476-5381
DOI:10.1111/bph.14910
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1111/bph.14910
Verlag, lizenzpflichtig, Volltext: https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14910
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Author Notes:Olga Zavaritskaya, Srikanth Dudem, Dongyu Ma, Kaneez E. Rabab, Sarah Albrecht, Dmitry Tsvetkov, Mario Kassmann, Keith Thornbury, Mitko Mladenov, Claire Kammermeier, Gerard Sergeant, Nicholas Mullins, Ornella Wouappi, Hannah Wurm, Aimo Kannt, Maik Gollasch, Mark A. Hollywood, Rudolf Schubert
Description
Summary:Background and Purpose - BK channels play important roles in various physiological and pathophysiological processes and thus have been the target of several drug development programmes focused on creating new efficacious BK channel openers, such as the GoSlo‐SR compounds.
Item Description:First published: 28 October 2019
Im Titel ist "v" bei "Kv7" tiefgestellt
Gesehen am 20.01.2021
Physical Description:Online Resource
ISSN:1476-5381
DOI:10.1111/bph.14910