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Three steps to gold: mechanism of protein adsorption revealed by Brownian and molecular dynamics simulations

The addition of three N-terminal histidines to β-lactamase inhibitor protein was shown experimentally to increase its binding potency to an Au(111) surface substantially but the binding mechanism was not resolved. Here, we propose a complete adsorption mechanism for this fusion protein by means of a...

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Main Authors: Özboyacı, Musa (Author) , Kokh, Daria B. (Author) , Wade, Rebecca C. (Author)
Format: Article (Journal)
Language:English
Published: 21 Mar 2016
In: Physical chemistry, chemical physics
Year: 2016, Volume: 18, Issue: 15, Pages: 10191-10200
ISSN:1463-9084
DOI:10.1039/C6CP00201C
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1039/C6CP00201C
Verlag, lizenzpflichtig, Volltext: https://pubs.rsc.org/en/content/articlelanding/2016/cp/c6cp00201c
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Author Notes:M. Ozboyaci, D.B. Kokh and R.C. Wade

MARC

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