Tumor type M2 pyruvate kinase (TuM2-PK) as a novel plasma tumor marker in melanoma

Proliferating cells express the pyruvate kinase isoenzyme type M2 (M2-PK). This enzyme exists as an active tetramer and an inactive dimer. The dimeric form is predominantly found in tumor cells and is therefore termed Tumor M2-PK (TuM2-PK). TuM2-PK molecules are released into the peripheral blood an...

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Bibliographic Details
Main Authors: Ugurel, Selma (Author) , Sucker, Antje (Author) , Rittgen, Werner (Author) , Schadendorf, Dirk (Author)
Format: Article (Journal)
Language:English
Published: 14 June 2005
In: International journal of cancer
Year: 2005, Volume: 117, Issue: 5, Pages: 825-830
ISSN:1097-0215
DOI:https://doi.org/10.1002/ijc.21073
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/https://doi.org/10.1002/ijc.21073
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.21073
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Author Notes:Selma Ugurel, Nellie Bell, Antje Sucker, Anette Zimpfer, Werner Rittgen and Dirk Schadendorf
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