Tumor type M2 pyruvate kinase (TuM2-PK) as a novel plasma tumor marker in melanoma
Proliferating cells express the pyruvate kinase isoenzyme type M2 (M2-PK). This enzyme exists as an active tetramer and an inactive dimer. The dimeric form is predominantly found in tumor cells and is therefore termed Tumor M2-PK (TuM2-PK). TuM2-PK molecules are released into the peripheral blood an...
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| Main Authors: | , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
14 June 2005
|
| In: |
International journal of cancer
Year: 2005, Volume: 117, Issue: 5, Pages: 825-830 |
| ISSN: | 1097-0215 |
| DOI: | https://doi.org/10.1002/ijc.21073 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/https://doi.org/10.1002/ijc.21073 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.21073 |
| Author Notes: | Selma Ugurel, Nellie Bell, Antje Sucker, Anette Zimpfer, Werner Rittgen and Dirk Schadendorf |
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