Stereoselective synthesis of tetrazolo- spiroquinazolinone derivatives through one-pot pseudo six-component reaction
A stereoselective catalyst-free one-pot pseudo six-component reaction of isatoic anhydride, hydrazine hydrate, cyclic ketones, isocyanides and trimethylsilyl azide to yield a series of tetrazolo-spiroquinazolinone is described. The protocol offers the advantages of mild reaction conditions, one-pot...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
16 August 2016
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| In: |
Tetrahedron
Year: 2016, Volume: 72, Issue: 41, Pages: 6409-6414 |
| ISSN: | 1464-5416 |
| DOI: | 10.1016/j.tet.2016.08.046 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.tet.2016.08.046 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0040402016308225 
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| Author Notes: | Sorour Ramezanpour, Saeed Balalaie, Frank Rominger |
| Summary: | A stereoselective catalyst-free one-pot pseudo six-component reaction of isatoic anhydride, hydrazine hydrate, cyclic ketones, isocyanides and trimethylsilyl azide to yield a series of tetrazolo-spiroquinazolinone is described. The protocol offers the advantages of mild reaction conditions, one-pot operational simplicity, modest-good yields, easy work-up procedure, and environmental benignity. |
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| Item Description: | Dedicated to Professor Rolf Gleiter on the occasion of his 80th birthday Gesehen am 17.02.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1464-5416 |
| DOI: | 10.1016/j.tet.2016.08.046 |