Exocyclic DNA adducts as biomarkers for oxidative stress, dietary risk factors and cancer chemopreventive approaches

This chapter contains sections titled: Exocyclic DNA Adducts as Biomarkers for Oxidative Stress, Dietary Risk Factors and Cancer Chemopreventive Approaches Abstract Introduction Results and discussion Increased exocyclic adduct formation as a consequence of LPO Etheno adducts Malondialdehyde-dG and...

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Hauptverfasser: Bartsch, Helmut (VerfasserIn) , Nair, Jagadeesan (VerfasserIn)
Dokumenttyp: Kapitel/Artikel Konferenzschrift
Sprache:Englisch
Veröffentlicht: 17 July 2000
In: Carcinogenic and anticarcinogenic factors in food
Year: 2000, Pages: 396-403
DOI:10.1002/3527606246.ch3e
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/3527606246.ch3e
Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1002/3527606246.ch3e
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Verfasserangaben:Helmut Bartsch and J. Nair

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520 |a This chapter contains sections titled: Exocyclic DNA Adducts as Biomarkers for Oxidative Stress, Dietary Risk Factors and Cancer Chemopreventive Approaches Abstract Introduction Results and discussion Increased exocyclic adduct formation as a consequence of LPO Etheno adducts Malondialdehyde-dG and propano-dG adducts Perspectives Biological Markers in Chemoprevention Research Abstract Introduction Validation studies Inter- and intra-individual variation Transitional studies: Nutritional and genetic factors and DNA damage PAH-DNA as a marker of lung cancer risk Nutritional status and lung cancer risk Genetic susceptibility to carcinogen exposure Early vs intermediate markers Modulation of biomarkers in an antioxidant vitamin trial in smokers Conclusions 
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