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RNA Exosome

Assembling work by prominent researchers in the field of RNA exosomes, this excellent introduction to the fascinating protein complex provides a comprehensive account of the proteins' many functions as well as a historical account of the field's development.

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Bibliographic Details
Other Authors: Jensen, Torben Heick (Editor)
Format: Book/Monograph
Language:English
Published: New York, NY Springer New York 2010
Series:Advances in experimental medicine and biology volume 702
In: Advances in experimental medicine and biology (volume 702)

Volumes / Articles: Show Volumes / Articles.
Online Access:Aggregator, lizenzpflichtig: https://ebookcentral.proquest.com/lib/kxp/detail.action?docID=763681
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Author Notes:editors: Torben Heick Jensen

MARC

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520 |a Assembling work by prominent researchers in the field of RNA exosomes, this excellent introduction to the fascinating protein complex provides a comprehensive account of the proteins' many functions as well as a historical account of the field's development. 
520 |a Intro -- Title Page -- Copyright Page -- PREFACE -- ABOUT THE EDITOR... -- PARTICIPANTS -- Table of Contents -- CHAPTER 1 FINDING THE EXOSOME -- Abstract -- INTRODUCTION -- FROM NORTHERNS TO NUCLEASES -- A GLIMPSE OF THE EXOSOME -- THE COMPLETE COMPLEX -- A BROADER PERSPECTIVE -- CONCLUSION -- ACKNOWLEDGEMENTS -- REFERENCES -- CHAPTER 2 STRUCTURAL COMPONENTS AND ARCHITECTURES OF RNA EXOSOMES -- Abstract -- INTRODUCTION -- GLOBAL STRUCTURE OF THE EXOSOME -- RNase PH-LIKE DOMAINS IN BACTERIAL, ARCHAEAL AND EUKARYOTIC CORE EXOSOMES -- S1 AND KH CONTAINING DOMAINS IN BACTERIAL, ARCHAEAL AND EUKARYOTIC CORE EXOSOMES -- MECHANISM OF PHOSPHOROLYTIC ACTIVITY IN BACTERIAL PNPase AND ARCHAEAL EXOSOMES -- Rrp44, A EUKARYOTIC EXOSOME SUBUNIT WITH HYDROLYTIC ENDORIBONUCLEASE AND PROCESSIVE EXORIBONUCLEASE ACTIVITIES -- Rrp44 PIN DOMAIN -- Rrp44 RNB DOMAIN -- Rrp44 AND THE 10-COMPONENT EXOSOME -- Rrp6, A EUKARYOTIC EXOSOME SUBUNIT WITH DISTRIBUTIVE HYDROLYTIC ACTIVITIES -- Rrp6 INTERACTIONS WITH THE EXOSOME CORE -- CONCLUSION -- ACKNOWLEDGEMENTS -- REFERENCES -- CHAPTER 3 THE ARCHAEAL EXOSOME -- Abstract -- INTRODUCTION -- CORE SUBUNITS OF THE ARCHAEAL EXOSOME -- STRUCTURE AND MECHANISM -- The Catalytically Active RPD-Hexamer -- The Flexible RNA-Binding Cap -- PHYSIOLOGICAL FUNCTIONS -- CONCLUSION -- ACKNOWLEDGEMENTS -- NOTE ADDED IN PROOF -- REFERENCES -- CHAPTER 4 THE EXOSOMES OF TRYPANOSOMES AND OTHER PROTISTS -- Abstract -- INTRODUCTION -- TRYPANOSOMES AS A MODEL SYSTEM FOR RNA PROCESSING AND TURNOVER -- THE STRUCTURE OF THE TRYPANOSOME EXOSOME -- THE POSITION OF RRP6 RELATIVE TO THE EXOSOME CORE -- FUNCTIONS OF THE TRYPANOSOME EXOSOME IN THE NUCLEUS -- FUNCTIONS OF THE TRYPANOSOME EXOSOME IN THE CYTOPLASM -- CONSERVATION OF THE EXOSOME IN EUKARYOTIC EVOLUTION -- CONCLUSION -- ACKNOWLEDGEMENTS -- REFERENCES. 
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