Hypofractionated carbon ion therapy delivered with scanned ion beams for patients with hepatocellular carcinoma: feasibility and clinical response
Photon-based radiation therapy does currently not play a major role as local ablative treatment for hepatocellular carcinoma (HCC). Carbon ions offer distinct physical and biological advantages. Due to their inverted dose profile and the high local dose deposition within the Bragg peak, precise dose...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
13 March 2013
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| In: |
Radiation oncology
Year: 2013, Volume: 8 |
| ISSN: | 1748-717X |
| DOI: | 10.1186/1748-717X-8-59 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1748-717X-8-59
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| Author Notes: | Daniel Habermehl, Jürgen Debus, Tom Ganten, Maria-Katharina Ganten, Julia Bauer, Ingo C. Brecht, Stephan Brons, Thomas Haberer, Martin Haertig, Oliver Jäkel, Katia Parodi, Thomas Welzel and Stephanie E. Combs |
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| 520 | |a Photon-based radiation therapy does currently not play a major role as local ablative treatment for hepatocellular carcinoma (HCC). Carbon ions offer distinct physical and biological advantages. Due to their inverted dose profile and the high local dose deposition within the Bragg peak, precise dose application and sparing of normal tissue is possible. Furthermore, carbon ions have an increased relative biological effectiveness (RBE) compared to photons. | ||
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