Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34
Here we identified the human serine/threonine kinase HIPK2 as a novel member of the DYRK kinase subfamily. Alignment of several DYRK family proteins including the kinases minibrain, MJAK, PKY, the Dictyostelium kinase YakA and Saccharomyces YAK1 allowed the identification of several evolutionary con...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
18 December 2000
|
| In: |
Biochimie
Year: 2000, Jahrgang: 82, Heft: 12, Pages: 1123-1127 |
| DOI: | 10.1016/S0300-9084(00)01196-2 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/S0300-9084(00)01196-2 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0300908400011962 
|
| Verfasserangaben: | Thomas G Hofmann, Antoaneta Mincheva, Peter Lichter, Wulf Dröge, M Lienhard Schmitz |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1747185957 | ||
| 003 | DE-627 | ||
| 005 | 20220819093800.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 210203s2000 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/S0300-9084(00)01196-2 |2 doi | |
| 035 | |a (DE-627)1747185957 | ||
| 035 | |a (DE-599)KXP1747185957 | ||
| 035 | |a (OCoLC)1341390285 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Hofmann, Thomas G. |d 1971- |e VerfasserIn |0 (DE-588)1161034552 |0 (DE-627)1024442586 |0 (DE-576)506322572 |4 aut | |
| 245 | 1 | 0 | |a Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34 |c Thomas G Hofmann, Antoaneta Mincheva, Peter Lichter, Wulf Dröge, M Lienhard Schmitz |
| 264 | 1 | |c 18 December 2000 | |
| 300 | |a 5 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 03.02.2021 | ||
| 520 | |a Here we identified the human serine/threonine kinase HIPK2 as a novel member of the DYRK kinase subfamily. Alignment of several DYRK family proteins including the kinases minibrain, MJAK, PKY, the Dictyostelium kinase YakA and Saccharomyces YAK1 allowed the identification of several evolutionary conserved DYRK consensus motifs within the kinase domain. A lysine residue conserved between all DYRK kinase family members was found to be essential for the kinase function of HIPK2. Human HIPK2 was mapped to chromosome 7q32-q34 and murine HIPK2 to chromosome 6B, the homologue to human chromosome 7. | ||
| 650 | 4 | |a chromosomal localization | |
| 650 | 4 | |a HIPK2 | |
| 650 | 4 | |a phosphorylation | |
| 650 | 4 | |a protein kinase | |
| 700 | 1 | |a Mincheva, Antoaneta |e VerfasserIn |0 (DE-588)1226242642 |0 (DE-627)1747183989 |4 aut | |
| 700 | 1 | |a Lichter, Peter |d 1957- |e VerfasserIn |0 (DE-588)1096366282 |0 (DE-627)856749915 |0 (DE-576)468019049 |4 aut | |
| 700 | 1 | |a Dröge, Wulf |d -2011 |e VerfasserIn |0 (DE-588)1178587789 |0 (DE-627)1049465539 |0 (DE-576)517837528 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Biochimie |d Paris [u.a.] : Elsevier, 1971 |g 82(2000), 12, Seite 1123-1127 |h Online-Ressource |w (DE-627)320496945 |w (DE-600)2011725-5 |w (DE-576)094142157 |7 nnas |a Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34 |
| 773 | 1 | 8 | |g volume:82 |g year:2000 |g number:12 |g pages:1123-1127 |g extent:5 |a Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34 |
| 856 | 4 | 0 | |u https://doi.org/10.1016/S0300-9084(00)01196-2 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/article/pii/S0300908400011962 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20210203 | ||
| 993 | |a Article | ||
| 994 | |a 2000 | ||
| 998 | |g 1178587789 |a Dröge, Wulf |m 1178587789:Dröge, Wulf |d 50000 |e 50000PD1178587789 |k 0/50000/ |p 4 | ||
| 998 | |g 1096366282 |a Lichter, Peter |m 1096366282:Lichter, Peter |d 50000 |e 50000PL1096366282 |k 0/50000/ |p 3 | ||
| 998 | |g 1226242642 |a Mincheva, Antoaneta |m 1226242642:Mincheva, Antoaneta |d 50000 |e 50000PM1226242642 |k 0/50000/ |p 2 | ||
| 998 | |g 1161034552 |a Hofmann, Thomas G. |m 1161034552:Hofmann, Thomas G. |p 1 |x j | ||
| 999 | |a KXP-PPN1747185957 |e 3848294672 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"language":["eng"],"name":{"displayForm":["Thomas G Hofmann, Antoaneta Mincheva, Peter Lichter, Wulf Dröge, M Lienhard Schmitz"]},"note":["Gesehen am 03.02.2021"],"recId":"1747185957","person":[{"family":"Hofmann","role":"aut","display":"Hofmann, Thomas G.","given":"Thomas G."},{"role":"aut","family":"Mincheva","given":"Antoaneta","display":"Mincheva, Antoaneta"},{"given":"Peter","display":"Lichter, Peter","family":"Lichter","role":"aut"},{"display":"Dröge, Wulf","given":"Wulf","family":"Dröge","role":"aut"}],"id":{"doi":["10.1016/S0300-9084(00)01196-2"],"eki":["1747185957"]},"physDesc":[{"extent":"5 S."}],"title":[{"title":"Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34","title_sort":"Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"origin":[{"dateIssuedKey":"2000","dateIssuedDisp":"18 December 2000"}],"relHost":[{"recId":"320496945","origin":[{"publisher":"Elsevier","dateIssuedDisp":"1971-","dateIssuedKey":"1971","publisherPlace":"Paris [u.a.]"}],"title":[{"title_sort":"Biochimie","title":"Biochimie","subtitle":"an international journal of biochemistry and molecular biology"}],"id":{"eki":["320496945"],"zdb":["2011725-5"]},"physDesc":[{"extent":"Online-Ressource"}],"pubHistory":["53.1971 - 95.2013; Vol. 96.2014 -"],"note":["Gesehen am 09.11.2020"],"language":["eng"],"part":{"volume":"82","year":"2000","issue":"12","pages":"1123-1127","extent":"5","text":"82(2000), 12, Seite 1123-1127"},"disp":"Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34Biochimie","type":{"media":"Online-Ressource","bibl":"periodical"}}]} | ||
| SRT | |a HOFMANNTHOHUMANHOMEO1820 | ||