Dose-intensified bi-weekly temozolomide in patients with asymptomatic brain metastases from malignant melanoma: a phase II DeCOG/ADO study

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Background: Temozolomide has shown some efficacy in metastatic melanoma and recently received extended approval to treat brain tumours. The purpose of this study was to test a dose-intensified regimen of temozolomide in melanoma patients with brain metastases in a prospective, open-label, multicentr...

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Bibliographic Details
Main Authors:	Schadendorf, Dirk (Author) , Ugurel, Selma (Author) , Figl, Adina (Author)
Format:	Article (Journal)
Language:	English
Published:	2006
In:	Annals of oncology Year: 2006, Volume: 17, Issue: 10, Pages: 1592-1597
ISSN:	1569-8041
DOI:	10.1093/annonc/mdl148
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1093/annonc/mdl148 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0923753419473195
Author Notes:	D. Schadendorf, A. Hauschild, S. Ugurel, A. Thoelke, F. Egberts, M. Kreissig, R. Linse, U. Trefzer, T. Vogt, W. Tilgen, P. Mohr & C. Garbe

Dacarbazine, Cisplatin, and Interferon-alfa-2b with or without Interleukin-2 in metastatic melanoma: a randomized phase III trial (18951) of the European Organisation for Research... by Keilholz, Ulrich (Author) , Schadendorf, Dirk (Author) ,

in: Journal of clinical oncology, 23 (2005), 27, Seite 6747-6755

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Prospective randomized trial of interferon Alfa-2b and Interleukin-2 as adjuvant treatment for resected intermediate- and high-risk primary melanoma without clinically detectable n... by Hauschild, Axel (Author) , Schadendorf, Dirk (Author) ,

in: Journal of clinical oncology, 21 (2003), 15, Seite 2883-2888

Article (Journal) Online Resource

Patterns of constitutive and IFN-γ inducible expression of HLA class II molecules in human melanoma cell lines by Rodríguez, Teresa (Author) , Méndez, Roman (Author) , Schadendorf, Dirk (Author) ,

in: Immunogenetics, 59 (2007,2) Artikelnummer 123, 11 Seiten

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Differences in global gene expression in melanoma cell lines with and without homozygous deletion of the CDKN2A locus genes by Blöthner, Sandra (Author) , Hemminki, Kari (Author) , Chen, Bowang (Author) , Ugurel, Selma (Author) , Schadendorf, Dirk (Author) , Kumar, Rajiv (Author) ,

in: Melanoma research, 16 (2006), 4, Seite 297-307

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In vitro drug sensitivity predicts response and survival after individualized sensitivity-directed chemotherapy in metastatic melanoma: a multicenter phase II trial of the Dermatol... by Ugurel, Selma (Author) , Schadendorf, Dirk (Author) , Figl, Adina (Author) , Rittgen, Werner (Author) , Delorme, Stefan (Author) ,

in: Clinical cancer research, 12 (2006), 18, Seite 5454-5463

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Tumor type M2 pyruvate kinase (TuM2-PK) as a novel plasma tumor marker in melanoma by Ugurel, Selma (Author) , Sucker, Antje (Author) , Rittgen, Werner (Author) , Schadendorf, Dirk (Author) ,

in: International journal of cancer, 117 (2005), 5, Seite 825-830

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Clinical phase II study of pegylated liposomal doxorubicin as second-line treatment in disseminated melanoma by Fink, Wolfram (Author) , Figl, Adina (Author) , Figl, Robert (Author) , Ugurel, Selma (Author) , Schadendorf, Dirk (Author) ,

in: Onkologie, 27 (2004), 6, Seite 540-544

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Down-regulation of HLA class II and costimulatory CD86/B7-2 on circulating monocytes from melanoma patients by Ugurel, Selma (Author) , Schadendorf, Dirk (Author) ,

in: Cancer immunology immunotherapy, 53 (2004), 6, Seite 551-559

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Identification of known and novel immunogenic T-cell epitopes from tumor antigens recognized by peripheral blood T cells from patients responding to IL-2-based treatment by Scheibenbogen, Carmen (Author) , Song, Mingxia (Author) , Schadendorf, Dirk (Author) ,

in: International journal of cancer, 98 (2002), 3, Seite 409-414

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Treatment of disseminated ocular melanoma with sequential fotemustine, interferon α, and interleukin 2 by Becker, Jürgen C. (Author) , Schadendorf, Dirk (Author) ,

in: British journal of cancer, 87 (2002), 8, Seite 840-845

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