Inhibition of tyrosine phosphatases antagonizes CD95‐mediated apoptosis
Ligation of the CD95 receptor resulted in a transient increase of cellular tyrosine phosphorylation. The inhibition of protein tyrosine phosphatases by pervanadate, a potent activator of B cells and T cells through the induction of tyrosine phosphorylation and downstream signaling events in the acti...
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| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
25 December 2001
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| In: |
EJB
Year: 1999, Jahrgang: 264, Heft: 1, Pages: 132-139 |
| ISSN: | 1432-1033 |
| DOI: | 10.1046/j.1432-1327.1999.00587.x |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1046/j.1432-1327.1999.00587.x Verlag, lizenzpflichtig, Volltext: https://febs.onlinelibrary.wiley.com/doi/10.1046/j.1432-1327.1999.00587.x 
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| Verfasserangaben: | Steffen P. Hehner, Thomas G. Hofmann, Frank Ratter, Wulf Dröge and M. Lienhard Schmitz |
| Zusammenfassung: | Ligation of the CD95 receptor resulted in a transient increase of cellular tyrosine phosphorylation. The inhibition of protein tyrosine phosphatases by pervanadate, a potent activator of B cells and T cells through the induction of tyrosine phosphorylation and downstream signaling events in the activation cascade, antagonized CD95‐triggered apoptosis. |
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| Beschreibung: | First published: 25 December 2001 Elektronische Reproduktion der Druck-Ausgabe Gesehen am 09.02.2021 |
| Beschreibung: | Online Resource |
| ISSN: | 1432-1033 |
| DOI: | 10.1046/j.1432-1327.1999.00587.x |