Validation of a blood protein signature for non-small cell lung cancer
CT screening for lung cancer is effective in reducing mortality, but there are areas of concern, including a positive predictive value of 4% and development of interval cancers. A blood test that could manage these limitations would be useful, but development of such tests has been impaired by varia...
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| Hauptverfasser: | , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
1 August 2014
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| In: |
Clinical proteomics
Year: 2014, Jahrgang: 11 |
| ISSN: | 1559-0275 |
| DOI: | 10.1186/1559-0275-11-32 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1559-0275-11-32
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| Verfasserangaben: | Michael R. Mehan, Stephen A. Williams, Jill M. Siegfried, William L. Bigbee, Joel L. Weissfeld, David O. Wilson, Harvey I. Pass, William N. Rom, Thomas Muley, Michael Meister, Wilbur Franklin, York E. Miller, Edward N. Brody and Rachel M. Ostroff |
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| 520 | |a CT screening for lung cancer is effective in reducing mortality, but there are areas of concern, including a positive predictive value of 4% and development of interval cancers. A blood test that could manage these limitations would be useful, but development of such tests has been impaired by variations in blood collection that may lead to poor reproducibility across populations. | ||
| 650 | 4 | |a Biomarker | |
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| 700 | 1 | |a Brody, Edward N. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ostroff, Rachel M. |e VerfasserIn |4 aut | |
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