Production of recombinant H1 parvovirus stocks devoid of replication-competent viruses

Vector and helper plasmids for the production of recombinant H1 (rH1) parvovirus, an oncolytic virus and candidate vector for cancer gene therapy, were constructed with the aim of reducing the contamination of these preparations with replication-competent viruses (RCV). Split-helper plasmid...

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Bibliographic Details
Main Authors: Brown, Caroline S. (Author) , Rommelaere, Jean (Author) , Dinsart, Christiane (Author)
Format: Article (Journal)
Language:English
Published: December 10, 2002
In: Human gene therapy
Year: 2002, Volume: 13, Issue: 18, Pages: 2135-2145
ISSN:1557-7422
DOI:10.1089/104303402320987833
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1089/104303402320987833
Verlag, lizenzpflichtig, Volltext: https://www.liebertpub.com/doi/10.1089/104303402320987833
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Author Notes:Caroline S. Brown, Franca M. DiSumma, Jean Rommelaere, Alexandra Y. Dege, Jan J. Cornelis, Christiane Dinsart, and Willy J.M. Spaan
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