Chimeric and pseudotyped parvoviruses minimize the contamination of recombinant stocks with replication-competent viruses and Iidentify a DNA sequence that restricts parvovirus H-1 in mouse cells

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Recent studies demonstrated the ability of the recombinant autonomous parvoviruses MVMp (fibrotropic variant of the minute virus of mice) and H-1 to transduce therapeutic genes in tumor cells. However, recombinant vector stocks are contaminated by replication-competent viruses (RCVs) generated durin...

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Bibliographic Details
Main Authors:	Wrzesinski, Claudia (Author) , Salomé, Nathalie (Author) , Rommelaere, Jean (Author) , Dinsart, Christiane (Author)
Format:	Article (Journal)
Language:	English
Published:	March 15, 2003
In:	Journal of virology Year: 2003, Volume: 77, Issue: 6, Pages: 3851-3858
ISSN:	1098-5514
DOI:	10.1128/JVI.77.6.3851-3858.2003
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1128/JVI.77.6.3851-3858.2003 Verlag, lizenzpflichtig, Volltext: https://jvi.asm.org/content/77/6/3851
Author Notes:	Claudia Wrzesinski, Lia Tesfay, Nathalie Salomé, Jean-Claude Jauniaux, Jean Rommelaere, Jan Cornelis, and Christiane Dinsart

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Expression profiling of human hepatoma cells reveals global repression of genes involved in cell proliferation, growth, and apoptosis upon infection with parvovirus H-1 by Li, Jianhong (Author) , Rommelaere, Jean (Author) ,

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Parvovirus H-1 infection of human glioma cells leads to complete viral replication and efficient cell killing by Herrero y Calle, Marta (Author) , Herold-Mende, Christel (Author) , Rommelaere, Jean (Author) , Schlehofer, Jörg R. (Author) , Geletneky, Karsten (Author) ,

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Novel PKCη is required to activate replicative functions of the major nonstructural protein NS1 of minute virus of mice by Lachmann, Sylvie (Author) , Rommelaere, Jean (Author) , Nüesch, Jürg P. F. (Author) ,

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Oncolytic parvovirus H1 induces release of heat-shock protein HSP72 in susceptible human tumor cells but may not affect primary immune cells by Möhler, Markus (Author) , Rommelaere, Jean (Author) ,

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Production of recombinant H1 parvovirus stocks devoid of replication-competent viruses by Brown, Caroline S. (Author) , Rommelaere, Jean (Author) , Dinsart, Christiane (Author) ,

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Regulation of MVM NS1 by protein kinase C: Impact of mutagenesis at consensus phosphorylation sites on replicative functions and cytopathic effects by Corbau, Romuald (Author) , Rommelaere, Jean (Author) , Nüesch, Jürg P. F. (Author) ,

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Effective infection, apoptotic cell killing and gene transfer of human hepatoma cells but not primary hepatocytes by parvovirus H1 and derived vectors by Möhler, Markus (Author) , Stremmel, Wolfgang (Author) , Rommelaere, Jean (Author) ,

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Inhibition of transcription-regulating properties of nonstructural protein 1 (NS1) of parvovirus minute virus of mice by a dominant-negative mutant form of NS1 by Deleu, Laurent (Author) , Nüesch, Jürg P. F. (Author) , Rommelaere, Jean (Author) ,

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Experimentally induced infection with autonomous parvoviruses, minute virus of mice and H-1, in the african multimammate mouse (Mastomys coucha) by Haag, Andreas (Author) , Rommelaere, Jean (Author) ,

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DNA unwinding functions of minute virus of mice NS1 protein are modulated specifically by the lambda isoform of protein kinase C by Dettwiler, Sabine (Author) , Rommelaere, Jean (Author) , Nüesch, Jürg P. F. (Author) ,

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Parvovirus H-1-induced cell death: influence of intracellular NAD consumption on the regulation of necrosis and apoptosis by Ran, Zhi-Hua (Author) , Rommelaere, Jean (Author) ,

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