Oncolytic parvovirus H1 induces release of heat-shock protein HSP72 in susceptible human tumor cells but may not affect primary immune cells

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Certain autonomous parvoviruses preferentially replicate in and kill in vitro-transformed cells and may reduce the incidence of spontaneous and implanted tumors in animals. Hence, these viruses and their derivatives are currently under evaluation as antitumor vectors. However, the mechanisms underly...

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Bibliographische Detailangaben
Hauptverfasser:	Möhler, Markus (VerfasserIn) , Rommelaere, Jean (VerfasserIn)
Dokumenttyp:	Article (Journal)
Sprache:	Englisch
Veröffentlicht:	27 May 2003
In:	Cancer gene therapy Year: 2003, Jahrgang: 10, Heft: 6, Pages: 477-480
ISSN:	1476-5500
DOI:	10.1038/sj.cgt.7700591
Online-Zugang:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/sj.cgt.7700591 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/7700591
Verfasserangaben:	Markus Moehler, Maja Zeidler, Joerg Schede, Jean Rommelaere, Peter R. Galle, Jan J. Cornelis, and Michael Heike

Parvovirus H1 selectively induces cytotoxic effects on human neuroblastoma cells von Lacroix, Jeannine (VerfasserIn) , Leuchs, Barbara (VerfasserIn) , Li, Junwei (VerfasserIn) , Hristov, Georgi (VerfasserIn) , Deubzer, Hedwig E. (VerfasserIn) , Kulozik, Andreas (VerfasserIn) , Rommelaere, Jean (VerfasserIn) , Schlehofer, Jörg R. (VerfasserIn) , Witt, Olaf (VerfasserIn) ,

in: International journal of cancer, 127 (2010), 5, Seite 1230-1239

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Expression profiling of human hepatoma cells reveals global repression of genes involved in cell proliferation, growth, and apoptosis upon infection with parvovirus H-1 von Li, Jianhong (VerfasserIn) , Rommelaere, Jean (VerfasserIn) ,

in: Journal of virology, 79 (2005), 4, Seite 2274-2286

Article (Journal) Online Resource

Parvovirus H-1 infection of human glioma cells leads to complete viral replication and efficient cell killing von Herrero y Calle, Marta (VerfasserIn) , Herold-Mende, Christel (VerfasserIn) , Rommelaere, Jean (VerfasserIn) , Schlehofer, Jörg R. (VerfasserIn) , Geletneky, Karsten (VerfasserIn) ,

in: International journal of cancer, 109 (2004), 1, Seite 76-84

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Chimeric and pseudotyped parvoviruses minimize the contamination of recombinant stocks with replication-competent viruses and Iidentify a DNA sequence that restricts parvovirus H-1... von Wrzesinski, Claudia (VerfasserIn) , Salomé, Nathalie (VerfasserIn) , Rommelaere, Jean (VerfasserIn) , Dinsart, Christiane (VerfasserIn) ,

in: Journal of virology, 77 (2003), 6, Seite 3851-3858

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Novel PKCη is required to activate replicative functions of the major nonstructural protein NS1 of minute virus of mice von Lachmann, Sylvie (VerfasserIn) , Rommelaere, Jean (VerfasserIn) , Nüesch, Jürg P. F. (VerfasserIn) ,

in: Journal of virology, 77 (2003), 14, Seite 8048-8060

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Production of recombinant H1 parvovirus stocks devoid of replication-competent viruses von Brown, Caroline S. (VerfasserIn) , Rommelaere, Jean (VerfasserIn) , Dinsart, Christiane (VerfasserIn) ,

in: Human gene therapy, 13 (2002), 18, Seite 2135-2145

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Regulation of MVM NS1 by protein kinase C: Impact of mutagenesis at consensus phosphorylation sites on replicative functions and cytopathic effects von Corbau, Romuald (VerfasserIn) , Rommelaere, Jean (VerfasserIn) , Nüesch, Jürg P. F. (VerfasserIn) ,

in: Virology, 278 (2000), 1, Seite 151-167

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Effective infection, apoptotic cell killing and gene transfer of human hepatoma cells but not primary hepatocytes by parvovirus H1 and derived vectors von Möhler, Markus (VerfasserIn) , Stremmel, Wolfgang (VerfasserIn) , Rommelaere, Jean (VerfasserIn) ,

in: Cancer gene therapy, 8 (2001), 3, Seite 158-167

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Inhibition of transcription-regulating properties of nonstructural protein 1 (NS1) of parvovirus minute virus of mice by a dominant-negative mutant form of NS1 von Deleu, Laurent (VerfasserIn) , Nüesch, Jürg P. F. (VerfasserIn) , Rommelaere, Jean (VerfasserIn) ,

in: Journal of general virology, 82 (2001), 8, Seite 1929-1934

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Experimentally induced infection with autonomous parvoviruses, minute virus of mice and H-1, in the african multimammate mouse (Mastomys coucha) von Haag, Andreas (VerfasserIn) , Rommelaere, Jean (VerfasserIn) ,

in: Comparative medicine, 50 (2000), 6, Seite 613-621

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H-1 parvovirus-associated replication bodies: a distinct virus-induced nuclear structure von Cziepluch, Celina (VerfasserIn) , Lichter, Peter (VerfasserIn) , Rommelaere, Jean (VerfasserIn) ,

in: Journal of virology, 74 (2000), 10, Seite 4807-4815

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DNA unwinding functions of minute virus of mice NS1 protein are modulated specifically by the lambda isoform of protein kinase C von Dettwiler, Sabine (VerfasserIn) , Rommelaere, Jean (VerfasserIn) , Nüesch, Jürg P. F. (VerfasserIn) ,

in: Journal of virology, 73 (1999), 9, Seite 7410-7420

Article (Journal) Online Resource

Parvovirus H-1-induced cell death: influence of intracellular NAD consumption on the regulation of necrosis and apoptosis von Ran, Zhi-Hua (VerfasserIn) , Rommelaere, Jean (VerfasserIn) ,

in: Virus research, 65 (1999), 2, Seite 161-174

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