Buchumschlag

Cyclic stretch of either PNS or CNS located nerves can stimulate neurite outgrowth

The central nervous system (CNS) does not recover from traumatic axonal injury, but the peripheral nervous system (PNS) does. We hypothesize that this fundamental difference in regenerative capacity may be based upon the absence of stimulatory mechanical forces in the CNS due to the protective rigid...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kampanis, Vasileios (VerfasserIn) , Tolou Dabbaghian, Bahardokht (VerfasserIn) , Zhou, Luming (VerfasserIn) , Roth, Wolfgang (VerfasserIn) , Puttagunta, Radhika (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2021
In: Cells
Year: 2021, Jahrgang: 10, Heft: 1, Pages: 1-23
ISSN:2073-4409
DOI:10.3390/cells10010032
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/cells10010032
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2073-4409/10/1/32
Volltext
Verfasserangaben:Vasileios Kampanis, Bahardokht Tolou-Dabbaghian, Luming Zhou, Wolfgang Roth and Radhika Puttagunta

MARC

LEADER 00000caa a2200000 c 4500
001 1749195461
003 DE-627
005 20240723102753.0
007 cr uuu---uuuuu
008 210223s2021 xx |||||o 00| ||eng c
024 7 |a 10.3390/cells10010032  |2 doi 
035 |a (DE-627)1749195461 
035 |a (DE-599)KXP1749195461 
035 |a (OCoLC)1341395961 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Kampanis, Vasileios  |d 1992-  |e VerfasserIn  |0 (DE-588)1227969139  |0 (DE-627)1749195666  |4 aut 
245 1 0 |a Cyclic stretch of either PNS or CNS located nerves can stimulate neurite outgrowth  |c Vasileios Kampanis, Bahardokht Tolou-Dabbaghian, Luming Zhou, Wolfgang Roth and Radhika Puttagunta 
264 1 |c 2021 
300 |a 23 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Published: 28 December 2020 
500 |a Gesehen am 23.02.2021 
520 |a The central nervous system (CNS) does not recover from traumatic axonal injury, but the peripheral nervous system (PNS) does. We hypothesize that this fundamental difference in regenerative capacity may be based upon the absence of stimulatory mechanical forces in the CNS due to the protective rigidity of the vertebral column and skull. We developed a bioreactor to apply low-strain cyclic axonal stretch to adult rat dorsal root ganglia (DRG) connected to either the peripheral or central nerves in an explant model for inducing axonal growth. In response, larger diameter DRG neurons, mechanoreceptors and proprioceptors showed enhanced neurite outgrowth as well as increased Activating Transcription Factor 3 (ATF3). 
650 4 |a CNS 
650 4 |a cyclic stretch 
650 4 |a DRG 
650 4 |a mechanical loading 
650 4 |a neurite outgrowth 
650 4 |a PNS 
700 1 |a Tolou Dabbaghian, Bahardokht  |d 1993-  |e VerfasserIn  |0 (DE-588)1227969422  |0 (DE-627)1749196166  |4 aut 
700 1 |a Zhou, Luming  |e VerfasserIn  |4 aut 
700 1 |a Roth, Wolfgang  |e VerfasserIn  |0 (DE-588)1162961597  |0 (DE-627)1027052010  |0 (DE-576)507704568  |4 aut 
700 1 |a Puttagunta, Radhika  |e VerfasserIn  |0 (DE-588)1169091172  |0 (DE-627)1032729406  |0 (DE-576)511918240  |4 aut 
773 0 8 |i Enthalten in  |t Cells  |d Basel : MDPI, 2012  |g 10(2021), 1, Artikel-ID 32, Seite 1-23  |h Online-Ressource  |w (DE-627)718622081  |w (DE-600)2661518-6  |w (DE-576)365412112  |x 2073-4409  |7 nnas  |a Cyclic stretch of either PNS or CNS located nerves can stimulate neurite outgrowth 
773 1 8 |g volume:10  |g year:2021  |g number:1  |g elocationid:32  |g pages:1-23  |g extent:23  |a Cyclic stretch of either PNS or CNS located nerves can stimulate neurite outgrowth 
856 4 0 |u https://doi.org/10.3390/cells10010032  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://www.mdpi.com/2073-4409/10/1/32  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20210223 
993 |a Article 
994 |a 2021 
998 |g 1169091172  |a Puttagunta, Radhika  |m 1169091172:Puttagunta, Radhika  |d 910000  |d 911460  |e 910000PP1169091172  |e 911460PP1169091172  |k 0/910000/  |k 1/910000/911460/  |p 5  |y j 
998 |g 1162961597  |a Roth, Wolfgang  |m 1162961597:Roth, Wolfgang  |d 910000  |d 911460  |e 910000PR1162961597  |e 911460PR1162961597  |k 0/910000/  |k 1/910000/911460/  |p 4 
998 |g 1227969422  |a Tolou Dabbaghian, Bahardokht  |m 1227969422:Tolou Dabbaghian, Bahardokht  |d 910000  |d 911460  |e 910000PT1227969422  |e 911460PT1227969422  |k 0/910000/  |k 1/910000/911460/  |p 2 
998 |g 1227969139  |a Kampanis, Vasileios  |m 1227969139:Kampanis, Vasileios  |d 910000  |d 911460  |e 910000PK1227969139  |e 911460PK1227969139  |k 0/910000/  |k 1/910000/911460/  |p 1  |x j 
999 |a KXP-PPN1749195461  |e 3870916834 
BIB |a Y 
SER |a journal 
JSO |a {"name":{"displayForm":["Vasileios Kampanis, Bahardokht Tolou-Dabbaghian, Luming Zhou, Wolfgang Roth and Radhika Puttagunta"]},"origin":[{"dateIssuedDisp":"2021","dateIssuedKey":"2021"}],"id":{"doi":["10.3390/cells10010032"],"eki":["1749195461"]},"physDesc":[{"extent":"23 S."}],"relHost":[{"title":[{"title_sort":"Cells","subtitle":"open access journal","title":"Cells"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Cyclic stretch of either PNS or CNS located nerves can stimulate neurite outgrowthCells","note":["Gesehen am 09.05.12"],"language":["eng"],"recId":"718622081","pubHistory":["1.2012 -"],"part":{"issue":"1","pages":"1-23","year":"2021","extent":"23","text":"10(2021), 1, Artikel-ID 32, Seite 1-23","volume":"10"},"origin":[{"publisherPlace":"Basel","publisher":"MDPI","dateIssuedKey":"2012","dateIssuedDisp":"2012-"}],"id":{"zdb":["2661518-6"],"eki":["718622081"],"issn":["2073-4409"]},"physDesc":[{"extent":"Online-Ressource"}]}],"person":[{"family":"Kampanis","given":"Vasileios","roleDisplay":"VerfasserIn","display":"Kampanis, Vasileios","role":"aut"},{"role":"aut","display":"Tolou Dabbaghian, Bahardokht","roleDisplay":"VerfasserIn","given":"Bahardokht","family":"Tolou Dabbaghian"},{"given":"Luming","family":"Zhou","role":"aut","display":"Zhou, Luming","roleDisplay":"VerfasserIn"},{"display":"Roth, Wolfgang","roleDisplay":"VerfasserIn","role":"aut","family":"Roth","given":"Wolfgang"},{"family":"Puttagunta","given":"Radhika","display":"Puttagunta, Radhika","roleDisplay":"VerfasserIn","role":"aut"}],"title":[{"title_sort":"Cyclic stretch of either PNS or CNS located nerves can stimulate neurite outgrowth","title":"Cyclic stretch of either PNS or CNS located nerves can stimulate neurite outgrowth"}],"note":["Published: 28 December 2020","Gesehen am 23.02.2021"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"recId":"1749195461","language":["eng"]} 
SRT |a KAMPANISVACYCLICSTRE2021 

Ähnliche Einträge