Proinflammatory T cell polarization is already present in patients with early knee osteoarthritis
Investigating the pathophysiological mechanisms of early osteoarthritis (OA) is of utmost interest since this stage holds the strongest promise for therapeutic interventions. The aims of this study were to analyze if synovial inflammation is already present in early OA and to characterize the involv...
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| Hauptverfasser: | , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
22 January 2021
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| In: |
Arthritis Research & Therapy
Year: 2021, Jahrgang: 23 |
| ISSN: | 1465-9913 |
| DOI: | 10.1186/s13075-020-02410-w |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13075-020-02410-w Verlag, kostenfrei, Volltext: https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-020-02410-w 
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| Verfasserangaben: | Nils Rosshirt, Richard Trauth, Hadrian Platzer, Elena Tripel, Timo A. Nees, Hanns-Martin Lorenz, Theresa Tretter and Babak Moradi |
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| 520 | |a Investigating the pathophysiological mechanisms of early osteoarthritis (OA) is of utmost interest since this stage holds the strongest promise for therapeutic interventions. The aims of this study were to analyze if synovial inflammation is already present in early OA and to characterize the involved cell populations, by investigating synovial fluid (SF) and synovial membrane (SM) of early OA patients for the presence and polarization status of CD4 T cells. | ||
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