Zika virus infection in pregnancy: a protocol for the joint analysis of the prospective cohort studies of the ZIKAlliance, ZikaPLAN and ZIKAction consortia
Introduction Zika virus (ZIKV) infection in pregnancy has been associated with microcephaly and severe neurological damage to the fetus. Our aim is to document the risks of adverse pregnancy and birth outcomes and the prevalence of laboratory markers of congenital infection in deliveries to women ex...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
16 November 2020
|
| In: |
BMJ open
Year: 2020, Volume: 10, Issue: 12, Pages: 1-9 |
| ISSN: | 2044-6055 |
| DOI: | 10.1136/bmjopen-2019-035307 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1136/bmjopen-2019-035307 Verlag, lizenzpflichtig, Volltext: https://bmjopen.bmj.com/content/10/12/e035307 
|
| Author Notes: | A. E. Ades, Elizabeth B. Brickley, Neal Alexander, David Brown, Thomas Jaenisch, Demócrito de Barros Miranda-Filho, Moritz Pohl, Kerstin D. Rosenberger, Antoni Soriano-Arandes, Claire Thorne, Ricardo Arraes de Alencar Ximenes, Thalia Velho Barreto de Araújo, Vivian I. Avelino-Silva, Sarah Esperanza Bethencourt Castillo, Victor Hugo Borja Aburto, Patrícia Brasil, Celia D. C. Christie, Wayner Vieira de Souza, Jose Eduardo Gotuzzo H, Bruno Hoen, Marion Koopmans, Celina Maria Turchi Martelli, Mauro Martins Teixeira, Ernesto T. A. Marques, Maria Consuelo Miranda, Ulisses Ramos Montarroyos, Maria Elisabeth Moreira, J. Glenn Morris, Barry Rockx, Paola Mariela Saba Villarroel, Carmen Soria Segarra, Adriana Tami, Marília Dalva Turchi, Carlo Giaquinto, Xavier de Lamballerie, Annelies Wilder-Smith |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1750047950 | ||
| 003 | DE-627 | ||
| 005 | 20220819122932.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 210301s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1136/bmjopen-2019-035307 |2 doi | |
| 035 | |a (DE-627)1750047950 | ||
| 035 | |a (DE-599)KXP1750047950 | ||
| 035 | |a (OCoLC)1341396550 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Ades, Anthony E. |e VerfasserIn |0 (DE-588)1175962945 |0 (DE-627)1047092379 |0 (DE-576)516445375 |4 aut | |
| 245 | 1 | 0 | |a Zika virus infection in pregnancy |b a protocol for the joint analysis of the prospective cohort studies of the ZIKAlliance, ZikaPLAN and ZIKAction consortia |c A. E. Ades, Elizabeth B. Brickley, Neal Alexander, David Brown, Thomas Jaenisch, Demócrito de Barros Miranda-Filho, Moritz Pohl, Kerstin D. Rosenberger, Antoni Soriano-Arandes, Claire Thorne, Ricardo Arraes de Alencar Ximenes, Thalia Velho Barreto de Araújo, Vivian I. Avelino-Silva, Sarah Esperanza Bethencourt Castillo, Victor Hugo Borja Aburto, Patrícia Brasil, Celia D. C. Christie, Wayner Vieira de Souza, Jose Eduardo Gotuzzo H, Bruno Hoen, Marion Koopmans, Celina Maria Turchi Martelli, Mauro Martins Teixeira, Ernesto T. A. Marques, Maria Consuelo Miranda, Ulisses Ramos Montarroyos, Maria Elisabeth Moreira, J. Glenn Morris, Barry Rockx, Paola Mariela Saba Villarroel, Carmen Soria Segarra, Adriana Tami, Marília Dalva Turchi, Carlo Giaquinto, Xavier de Lamballerie, Annelies Wilder-Smith |
| 264 | 1 | |c 16 November 2020 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 01.03.2021 | ||
| 520 | |a Introduction Zika virus (ZIKV) infection in pregnancy has been associated with microcephaly and severe neurological damage to the fetus. Our aim is to document the risks of adverse pregnancy and birth outcomes and the prevalence of laboratory markers of congenital infection in deliveries to women experiencing ZIKV infection during pregnancy, using data from European Commission-funded prospective cohort studies in 20 centres in 11 countries across Latin America and the Caribbean. - Methods and analysis We will carry out a centre-by-centre analysis of the risks of adverse pregnancy and birth outcomes, comparing women with confirmed and suspected ZIKV infection in pregnancy to those with no evidence of infection in pregnancy. We will document the proportion of deliveries in which laboratory markers of congenital infection were present. Finally, we will investigate the associations of trimester of maternal infection in pregnancy, presence or absence of maternal symptoms of acute ZIKV infection and previous flavivirus infections with adverse outcomes and with markers of congenital infection. Centre-specific estimates will be pooled using a two-stage approach. - Ethics and dissemination Ethical approval was obtained at each centre. Findings will be presented at international conferences and published in peer-reviewed open access journals and discussed with local public health officials and representatives of the national Ministries of Health, Pan American Health Organization and WHO involved with ZIKV prevention and control activities. | ||
| 650 | 4 | |a epidemiology | |
| 650 | 4 | |a paediatric infectious disease & immunisation | |
| 650 | 4 | |a public health | |
| 700 | 1 | |a Brickley, Elizabeth B. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Alexander, Neal |e VerfasserIn |4 aut | |
| 700 | 1 | |a Brown, David |e VerfasserIn |4 aut | |
| 700 | 1 | |a Jänisch, Thomas |d 1968- |e VerfasserIn |0 (DE-588)121170993 |0 (DE-627)705277275 |0 (DE-576)182736911 |4 aut | |
| 700 | 1 | |a Miranda-Filho, Demócrito de Barros |e VerfasserIn |4 aut | |
| 700 | 1 | |a Pohl, Moritz |d 1991- |e VerfasserIn |0 (DE-588)1203763018 |0 (DE-627)1688817549 |4 aut | |
| 700 | 1 | |a Rosenberger, Kerstin |d 1982- |e VerfasserIn |0 (DE-588)1021668788 |0 (DE-627)715825933 |0 (DE-576)362818061 |4 aut | |
| 700 | 1 | |a Soriano-Arandes, Antoni |e VerfasserIn |4 aut | |
| 700 | 1 | |a Thorne, Claire |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ximenes, Ricardo Arraes de Alencar |e VerfasserIn |4 aut | |
| 700 | 1 | |a Araújo, Thalia Velho Barreto de |e VerfasserIn |4 aut | |
| 700 | 1 | |a Avelino-Silva, Vivian I. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Castillo, Sarah Esperanza Bethencourt |e VerfasserIn |4 aut | |
| 700 | 1 | |a Aburto, Victor Hugo Borja |e VerfasserIn |4 aut | |
| 700 | 1 | |a Brasil, Patrícia |e VerfasserIn |4 aut | |
| 700 | 1 | |a Christie, Celia D. C. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Souza, Wayner Vieira de |e VerfasserIn |4 aut | |
| 700 | 1 | |a H, Jose Eduardo Gotuzzo |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hoen, Bruno |e VerfasserIn |4 aut | |
| 700 | 1 | |a Koopmans, Marion |e VerfasserIn |4 aut | |
| 700 | 1 | |a Martelli, Celina Maria Turchi |e VerfasserIn |4 aut | |
| 700 | 1 | |a Teixeira, Mauro Martins |e VerfasserIn |4 aut | |
| 700 | 1 | |a Marques, Ernesto T. A. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Miranda, Maria Consuelo |e VerfasserIn |4 aut | |
| 700 | 1 | |a Montarroyos, Ulisses Ramos |e VerfasserIn |4 aut | |
| 700 | 1 | |a Moreira, Maria Elisabeth |e VerfasserIn |4 aut | |
| 700 | 1 | |a Morris, J. Glenn |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rockx, Barry |e VerfasserIn |4 aut | |
| 700 | 1 | |a Villarroel, Paola Mariela Saba |e VerfasserIn |4 aut | |
| 700 | 1 | |a Segarra, Carmen Soria |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tami, Adriana |e VerfasserIn |4 aut | |
| 700 | 1 | |a Turchi, Marília Dalva |e VerfasserIn |4 aut | |
| 700 | 1 | |a Giaquinto, Carlo |e VerfasserIn |4 aut | |
| 700 | 1 | |a Lamballerie, Xavier de |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wilder-Smith, Annelies |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t BMJ open |d London : BMJ Publishing Group, 2011 |g 10(2020,12) Artikel-Nummer e035307, 9 Seiten |h Online-Ressource |w (DE-627)654747075 |w (DE-600)2599832-8 |w (DE-576)339269340 |x 2044-6055 |7 nnas |a Zika virus infection in pregnancy a protocol for the joint analysis of the prospective cohort studies of the ZIKAlliance, ZikaPLAN and ZIKAction consortia |
| 773 | 1 | 8 | |g volume:10 |g year:2020 |g number:12 |g pages:1-9 |g extent:9 |a Zika virus infection in pregnancy a protocol for the joint analysis of the prospective cohort studies of the ZIKAlliance, ZikaPLAN and ZIKAction consortia |
| 856 | 4 | 0 | |u https://doi.org/10.1136/bmjopen-2019-035307 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://bmjopen.bmj.com/content/10/12/e035307 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20210301 | ||
| 993 | |a Article | ||
| 994 | |a 2020 | ||
| 998 | |g 1021668788 |a Rosenberger, Kerstin |m 1021668788:Rosenberger, Kerstin |d 910000 |d 911700 |e 910000PR1021668788 |e 911700PR1021668788 |k 0/910000/ |k 1/910000/911700/ |p 8 | ||
| 998 | |g 1203763018 |a Pohl, Moritz |m 1203763018:Pohl, Moritz |d 910000 |d 999701 |e 910000PP1203763018 |e 999701PP1203763018 |k 0/910000/ |k 1/910000/999701/ |p 4 | ||
| 998 | |g 121170993 |a Jänisch, Thomas |m 121170993:Jänisch, Thomas |d 910000 |d 912800 |d 50000 |e 910000PJ121170993 |e 912800PJ121170993 |e 50000PJ121170993 |k 0/910000/ |k 1/910000/912800/ |k 0/50000/ |p 5 | ||
| 999 | |a KXP-PPN1750047950 |e 3879788928 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"note":["Gesehen am 01.03.2021"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"recId":"1750047950","language":["eng"],"person":[{"role":"aut","roleDisplay":"VerfasserIn","display":"Ades, Anthony E.","given":"Anthony E.","family":"Ades"},{"given":"Elizabeth B.","family":"Brickley","role":"aut","display":"Brickley, Elizabeth B.","roleDisplay":"VerfasserIn"},{"roleDisplay":"VerfasserIn","display":"Alexander, Neal","role":"aut","family":"Alexander","given":"Neal"},{"display":"Brown, David","roleDisplay":"VerfasserIn","role":"aut","family":"Brown","given":"David"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Jänisch, Thomas","given":"Thomas","family":"Jänisch"},{"display":"Miranda-Filho, Demócrito de Barros","roleDisplay":"VerfasserIn","role":"aut","family":"Miranda-Filho","given":"Demócrito de Barros"},{"given":"Moritz","family":"Pohl","role":"aut","display":"Pohl, Moritz","roleDisplay":"VerfasserIn"},{"family":"Rosenberger","given":"Kerstin","roleDisplay":"VerfasserIn","display":"Rosenberger, Kerstin","role":"aut"},{"role":"aut","display":"Soriano-Arandes, Antoni","roleDisplay":"VerfasserIn","given":"Antoni","family":"Soriano-Arandes"},{"family":"Thorne","given":"Claire","display":"Thorne, Claire","roleDisplay":"VerfasserIn","role":"aut"},{"display":"Ximenes, Ricardo Arraes de Alencar","roleDisplay":"VerfasserIn","role":"aut","family":"Ximenes","given":"Ricardo Arraes de Alencar"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Araújo, Thalia Velho Barreto de","given":"Thalia Velho Barreto de","family":"Araújo"},{"role":"aut","display":"Avelino-Silva, Vivian I.","roleDisplay":"VerfasserIn","given":"Vivian I.","family":"Avelino-Silva"},{"display":"Castillo, Sarah Esperanza Bethencourt","roleDisplay":"VerfasserIn","role":"aut","family":"Castillo","given":"Sarah Esperanza Bethencourt"},{"family":"Aburto","given":"Victor Hugo Borja","display":"Aburto, Victor Hugo Borja","roleDisplay":"VerfasserIn","role":"aut"},{"display":"Brasil, Patrícia","roleDisplay":"VerfasserIn","role":"aut","family":"Brasil","given":"Patrícia"},{"role":"aut","display":"Christie, Celia D. C.","roleDisplay":"VerfasserIn","given":"Celia D. C.","family":"Christie"},{"role":"aut","display":"Souza, Wayner Vieira de","roleDisplay":"VerfasserIn","given":"Wayner Vieira de","family":"Souza"},{"family":"H","given":"Jose Eduardo Gotuzzo","display":"H, Jose Eduardo Gotuzzo","roleDisplay":"VerfasserIn","role":"aut"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Hoen, Bruno","given":"Bruno","family":"Hoen"},{"given":"Marion","family":"Koopmans","role":"aut","roleDisplay":"VerfasserIn","display":"Koopmans, Marion"},{"given":"Celina Maria Turchi","family":"Martelli","role":"aut","roleDisplay":"VerfasserIn","display":"Martelli, Celina Maria Turchi"},{"family":"Teixeira","given":"Mauro Martins","roleDisplay":"VerfasserIn","display":"Teixeira, Mauro Martins","role":"aut"},{"roleDisplay":"VerfasserIn","display":"Marques, Ernesto T. A.","role":"aut","family":"Marques","given":"Ernesto T. A."},{"family":"Miranda","given":"Maria Consuelo","roleDisplay":"VerfasserIn","display":"Miranda, Maria Consuelo","role":"aut"},{"role":"aut","display":"Montarroyos, Ulisses Ramos","roleDisplay":"VerfasserIn","given":"Ulisses Ramos","family":"Montarroyos"},{"role":"aut","display":"Moreira, Maria Elisabeth","roleDisplay":"VerfasserIn","given":"Maria Elisabeth","family":"Moreira"},{"given":"J. Glenn","family":"Morris","role":"aut","display":"Morris, J. Glenn","roleDisplay":"VerfasserIn"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Rockx, Barry","given":"Barry","family":"Rockx"},{"display":"Villarroel, Paola Mariela Saba","roleDisplay":"VerfasserIn","role":"aut","family":"Villarroel","given":"Paola Mariela Saba"},{"given":"Carmen Soria","family":"Segarra","role":"aut","roleDisplay":"VerfasserIn","display":"Segarra, Carmen Soria"},{"given":"Adriana","family":"Tami","role":"aut","display":"Tami, Adriana","roleDisplay":"VerfasserIn"},{"family":"Turchi","given":"Marília Dalva","roleDisplay":"VerfasserIn","display":"Turchi, Marília Dalva","role":"aut"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Giaquinto, Carlo","given":"Carlo","family":"Giaquinto"},{"role":"aut","display":"Lamballerie, Xavier de","roleDisplay":"VerfasserIn","given":"Xavier de","family":"Lamballerie"},{"given":"Annelies","family":"Wilder-Smith","role":"aut","roleDisplay":"VerfasserIn","display":"Wilder-Smith, Annelies"}],"title":[{"subtitle":"a protocol for the joint analysis of the prospective cohort studies of the ZIKAlliance, ZikaPLAN and ZIKAction consortia","title":"Zika virus infection in pregnancy","title_sort":"Zika virus infection in pregnancy"}],"physDesc":[{"extent":"9 S."}],"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"id":{"issn":["2044-6055"],"zdb":["2599832-8"],"eki":["654747075"]},"origin":[{"dateIssuedDisp":"2011-","publisher":"BMJ Publishing Group","dateIssuedKey":"2011","publisherPlace":"London"}],"part":{"year":"2020","pages":"1-9","issue":"12","volume":"10","text":"10(2020,12) Artikel-Nummer e035307, 9 Seiten","extent":"9"},"pubHistory":["2011 -"],"recId":"654747075","language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"note":["Gesehen am 02.10.20"],"disp":"Zika virus infection in pregnancy a protocol for the joint analysis of the prospective cohort studies of the ZIKAlliance, ZikaPLAN and ZIKAction consortiaBMJ open","title":[{"title_sort":"BMJ open","title":"BMJ open"}]}],"name":{"displayForm":["A. E. Ades, Elizabeth B. Brickley, Neal Alexander, David Brown, Thomas Jaenisch, Demócrito de Barros Miranda-Filho, Moritz Pohl, Kerstin D. Rosenberger, Antoni Soriano-Arandes, Claire Thorne, Ricardo Arraes de Alencar Ximenes, Thalia Velho Barreto de Araújo, Vivian I. Avelino-Silva, Sarah Esperanza Bethencourt Castillo, Victor Hugo Borja Aburto, Patrícia Brasil, Celia D. C. Christie, Wayner Vieira de Souza, Jose Eduardo Gotuzzo H, Bruno Hoen, Marion Koopmans, Celina Maria Turchi Martelli, Mauro Martins Teixeira, Ernesto T. A. Marques, Maria Consuelo Miranda, Ulisses Ramos Montarroyos, Maria Elisabeth Moreira, J. Glenn Morris, Barry Rockx, Paola Mariela Saba Villarroel, Carmen Soria Segarra, Adriana Tami, Marília Dalva Turchi, Carlo Giaquinto, Xavier de Lamballerie, Annelies Wilder-Smith"]},"origin":[{"dateIssuedKey":"2020","dateIssuedDisp":"16 November 2020"}],"id":{"eki":["1750047950"],"doi":["10.1136/bmjopen-2019-035307"]}} | ||
| SRT | |a ADESANTHONZIKAVIRUSI1620 | ||