Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: results from 108 lumbar punctures in 80 pediatric patients
New-generation, cell-based assays have demonstrated a robust association of serum autoantibodies to full-length human myelin oligodendrocyte glycoprotein (MOG-IgG) with (mostly recurrent) optic neuritis, myelitis, and brainstem encephalitis, as well as with neuromyelitis optica (NMO)-like or acute-d...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
03 September 2020
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| In: |
Journal of neuroinflammation
Year: 2020, Volume: 17, Issue: 1 |
| ISSN: | 1742-2094 |
| DOI: | 10.1186/s12974-020-01825-1 |
| Online Access: | Verlag, Volltext: https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-020-01825-1 Resolving-System, Volltext: https://doi.org/10.1186/s12974-020-01825-1 Verlag, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470445 
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| Author Notes: | Sven Jarius, Christian Lechner, Eva M. Wendel, Matthias Baumann, Markus Breu, Mareike Schimmel, Michael Karenfort, Adela Della Marina, Andreas Merkenschlager, Charlotte Thiels, Astrid Blaschek, Michela Salandin, Steffen Leiz, Frank Leypoldt, Alexander Pschibul, Annette Hackenberg, Andreas Hahn, Steffen Syrbe, Jurgis Strautmanis, Martin Häusler, Peter Krieg, Astrid Eisenkölbl, Johannes Stoffels, Matthias Eckenweiler, Ilya Ayzenberg, Jürgen Haas, Romana Höftberger, Ingo Kleiter,, Mirjam Korporal-Kuhnke, Marius Ringelstein,, Klemens Ruprecht, Nadja Siebert,, Kathrin Schanda, Orhan Aktas, Friedemann Paul,, Markus Reindl, Brigitte Wildemann and Kevin Rostásy; in cooperation with the BIOMARKER study group and the Neuromyelitis optica Study Group (NEMOS) |
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| 245 | 1 | 0 | |a Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2 |b results from 108 lumbar punctures in 80 pediatric patients |c Sven Jarius, Christian Lechner, Eva M. Wendel, Matthias Baumann, Markus Breu, Mareike Schimmel, Michael Karenfort, Adela Della Marina, Andreas Merkenschlager, Charlotte Thiels, Astrid Blaschek, Michela Salandin, Steffen Leiz, Frank Leypoldt, Alexander Pschibul, Annette Hackenberg, Andreas Hahn, Steffen Syrbe, Jurgis Strautmanis, Martin Häusler, Peter Krieg, Astrid Eisenkölbl, Johannes Stoffels, Matthias Eckenweiler, Ilya Ayzenberg, Jürgen Haas, Romana Höftberger, Ingo Kleiter,, Mirjam Korporal-Kuhnke, Marius Ringelstein,, Klemens Ruprecht, Nadja Siebert,, Kathrin Schanda, Orhan Aktas, Friedemann Paul,, Markus Reindl, Brigitte Wildemann and Kevin Rostásy; in cooperation with the BIOMARKER study group and the Neuromyelitis optica Study Group (NEMOS) |
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| 520 | |a New-generation, cell-based assays have demonstrated a robust association of serum autoantibodies to full-length human myelin oligodendrocyte glycoprotein (MOG-IgG) with (mostly recurrent) optic neuritis, myelitis, and brainstem encephalitis, as well as with neuromyelitis optica (NMO)-like or acute-disseminated encephalomyelitis (ADEM)-like presentations. However, only limited data are yet available on cerebrospinal fluid (CSF) findings in MOG-IgG-associated encephalomyelitis (MOG-EM; also termed MOG antibody-associated disease, MOGAD) | ||
| 650 | 4 | |a Acute disseminated encephalomyelitis (ADEM) | |
| 650 | 4 | |a Antibodies | |
| 650 | 4 | |a Brainstem encephalitis | |
| 650 | 4 | |a Cerebrospinal fluid | |
| 650 | 4 | |a Children | |
| 650 | 4 | |a Encephalomyelitis | |
| 650 | 4 | |a Lumbar puncture | |
| 650 | 4 | |a MOG antibody-associated disease (MOGAD) | |
| 650 | 4 | |a Multiple sclerosis (MS) | |
| 650 | 4 | |a Myelin oligodendrocyte glycoprotein (MOG) | |
| 650 | 4 | |a Neuromyelitis optica (Devic syndrome) | |
| 650 | 4 | |a NMO spectrum disorders | |
| 650 | 4 | |a Oligoclonal bands | |
| 650 | 4 | |a Optic neuritis | |
| 650 | 4 | |a Transverse myelitis | |
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